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Characteristics and Outcomes of Patients Receiving a Second Rescue Valve During Transcatheter Aortic Valve Implantation

Bjursten, Henrik LU ; Koul, Sasha LU ; Pétursson, Pétur ; Odenstedt, Jacob ; Hagström, Henrik ; Backes, Jenny ; Nielsen, Niels Erik ; Rück, Andreas ; Johansson, Jan and James, Stefan , et al. (2023) In Structural Heart
Abstract

Background: Transcatheter aortic valve implantation (TAVI) has become a safe procedure. However, complications occur, including uncommon complications such as valve malposition, which requires the implantation of an additional rescue valve (rescue-AV). The aim was to study the occurrence and outcomes of rescue-AV in a nationwide registry. Methods: The Swedish national TAVI registry was used as the primary data source, where all 6706 TAVI procedures from 2016 to 2021 were retrieved. Nontransfemoral access and planned valve-in-valve were excluded. In total, 79 patients were identified as having had a rescue-AV, and additional detailed data were collected for these patients. This dataset was analyzed for any characteristics that could... (More)

Background: Transcatheter aortic valve implantation (TAVI) has become a safe procedure. However, complications occur, including uncommon complications such as valve malposition, which requires the implantation of an additional rescue valve (rescue-AV). The aim was to study the occurrence and outcomes of rescue-AV in a nationwide registry. Methods: The Swedish national TAVI registry was used as the primary data source, where all 6706 TAVI procedures from 2016 to 2021 were retrieved. Nontransfemoral access and planned valve-in-valve were excluded. In total, 79 patients were identified as having had a rescue-AV, and additional detailed data were collected for these patients. This dataset was analyzed for any characteristics that could predispose patients to a rescue-AV. The outcome of patients receiving rescue-AV also was studied. Results: Of the 5948 patients in the study, 1.3% had a rescue-AV. There were few differences between patients receiving 1 valve and rescue-AV patients. For patients receiving a rescue-AV, the 30-day mortality was 15.2% compared to 1.6% in the control group. A poor outcome after rescue-AV was often associated with a second complication; for example, stroke, need for emergency surgery, or heart failure. Among the patients with rescue-AV who survived at least 30 days, landmark analyses showed similar survival rates compared to the control group. Conclusions: Among TAVI patients in a nationwide register, rescue-AV occurred in 1.3% of patients. The 30-day mortality in patients receiving rescue-AV was high, but long-term outcome among 30-day survivors was similar to the control group.

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organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Complication, Outcome, Survival, TAVI
in
Structural Heart
article number
100231
publisher
Taylor & Francis
external identifiers
  • scopus:85176929429
ISSN
2474-8706
DOI
10.1016/j.shj.2023.100231
language
English
LU publication?
yes
additional info
Funding Information: This work was supported by a regional government research fund under the agreement between the Swedish government and the county councils (ALF-agreement) and grants from the Swedish Heart-Lung Foundation . Publisher Copyright: © 2023 The Author(s)
id
acc75c42-b840-4776-be00-b398ff9d2249
date added to LUP
2023-11-29 20:49:07
date last changed
2024-02-27 19:42:59
@article{acc75c42-b840-4776-be00-b398ff9d2249,
  abstract     = {{<p>Background: Transcatheter aortic valve implantation (TAVI) has become a safe procedure. However, complications occur, including uncommon complications such as valve malposition, which requires the implantation of an additional rescue valve (rescue-AV). The aim was to study the occurrence and outcomes of rescue-AV in a nationwide registry. Methods: The Swedish national TAVI registry was used as the primary data source, where all 6706 TAVI procedures from 2016 to 2021 were retrieved. Nontransfemoral access and planned valve-in-valve were excluded. In total, 79 patients were identified as having had a rescue-AV, and additional detailed data were collected for these patients. This dataset was analyzed for any characteristics that could predispose patients to a rescue-AV. The outcome of patients receiving rescue-AV also was studied. Results: Of the 5948 patients in the study, 1.3% had a rescue-AV. There were few differences between patients receiving 1 valve and rescue-AV patients. For patients receiving a rescue-AV, the 30-day mortality was 15.2% compared to 1.6% in the control group. A poor outcome after rescue-AV was often associated with a second complication; for example, stroke, need for emergency surgery, or heart failure. Among the patients with rescue-AV who survived at least 30 days, landmark analyses showed similar survival rates compared to the control group. Conclusions: Among TAVI patients in a nationwide register, rescue-AV occurred in 1.3% of patients. The 30-day mortality in patients receiving rescue-AV was high, but long-term outcome among 30-day survivors was similar to the control group.</p>}},
  author       = {{Bjursten, Henrik and Koul, Sasha and Pétursson, Pétur and Odenstedt, Jacob and Hagström, Henrik and Backes, Jenny and Nielsen, Niels Erik and Rück, Andreas and Johansson, Jan and James, Stefan and Settergren, Magnus and Götberg, Matthias and Yndigen, Troels}},
  issn         = {{2474-8706}},
  keywords     = {{Complication; Outcome; Survival; TAVI}},
  language     = {{eng}},
  publisher    = {{Taylor & Francis}},
  series       = {{Structural Heart}},
  title        = {{Characteristics and Outcomes of Patients Receiving a Second Rescue Valve During Transcatheter Aortic Valve Implantation}},
  url          = {{http://dx.doi.org/10.1016/j.shj.2023.100231}},
  doi          = {{10.1016/j.shj.2023.100231}},
  year         = {{2023}},
}