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Algorithms for the treatment of motor problems in Parkinson's disease

Dietrichs, E and Odin, P. LU (2017) In Acta Neurologica Scandinavica 136(5). p.378-385
Abstract

Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algorithm suggests one way to treat PD from the first onset of motor symptoms. It is largely based on treatment recommendations from the Scandinavian countries and Germany. The other algorithm is meant as assistance for choosing among the different device-aided treatments for advanced PD. There is not sufficient comparative data to recommend one... (More)

Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algorithm suggests one way to treat PD from the first onset of motor symptoms. It is largely based on treatment recommendations from the Scandinavian countries and Germany. The other algorithm is meant as assistance for choosing among the different device-aided treatments for advanced PD. There is not sufficient comparative data to recommend one particular line of treatment, neither in early PD nor in advanced disease with motor complications. Individualized treatment is needed for each patient. The current algorithms only represent an alternative for aiding treatment decisions.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Apomorphine, Deep brain stimulation, Levodopa-carbidopa intestinal gel, Motor complications, Parkinson's disease, Treatment
in
Acta Neurologica Scandinavica
volume
136
issue
5
pages
378 - 385
publisher
Wiley-Blackwell
external identifiers
  • scopus:85011093319
  • pmid:28133726
  • wos:000415864000001
ISSN
0001-6314
DOI
10.1111/ane.12733
language
English
LU publication?
yes
id
ad26a071-8838-4847-bc20-bc577de5aed8
date added to LUP
2017-02-16 16:53:06
date last changed
2018-02-16 03:00:10
@article{ad26a071-8838-4847-bc20-bc577de5aed8,
  abstract     = {<p>Several different strategies are effective for medical treatment of motor problems in Parkinson's disease (PD). Many guidelines and evidence-based reviews are available, but there is no documentation or consensus in favor of just one treatment strategy. This review presents two algorithms that may be helpful when deciding how to treat a PD patient at various stages of the disease. The first algorithm suggests one way to treat PD from the first onset of motor symptoms. It is largely based on treatment recommendations from the Scandinavian countries and Germany. The other algorithm is meant as assistance for choosing among the different device-aided treatments for advanced PD. There is not sufficient comparative data to recommend one particular line of treatment, neither in early PD nor in advanced disease with motor complications. Individualized treatment is needed for each patient. The current algorithms only represent an alternative for aiding treatment decisions.</p>},
  author       = {Dietrichs, E and Odin, P.},
  issn         = {0001-6314},
  keyword      = {Apomorphine,Deep brain stimulation,Levodopa-carbidopa intestinal gel,Motor complications,Parkinson's disease,Treatment},
  language     = {eng},
  number       = {5},
  pages        = {378--385},
  publisher    = {Wiley-Blackwell},
  series       = {Acta Neurologica Scandinavica},
  title        = {Algorithms for the treatment of motor problems in Parkinson's disease},
  url          = {http://dx.doi.org/10.1111/ane.12733},
  volume       = {136},
  year         = {2017},
}