Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Protein biosynthesis in mitochondria

Kuzmenko, A. V. ; Levitskii, S. A. ; Vinogradova, E. N. ; Atkinson, G. C. LU ; Hauryliuk, V. LU orcid ; Zenkin, N. and Kamenski, P. A. (2013) In Biochemistry (Moscow) 78(8). p.855-866
Abstract

Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great detail. However, significantly less is known about translation in eukaryotic mitochondria, which is characterized by a number of unusual features. In this review, we summarize current knowledge about mitochondrial translation in different organisms while paying special attention to the aspects of this process that differ from cytoplasmic protein biosynthesis.

Please use this url to cite or link to this publication:
author
; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
keywords
mitochondria, ribosomes, translation, translation factors
in
Biochemistry (Moscow)
volume
78
issue
8
pages
855 - 866
publisher
Pleiades Publishing
external identifiers
  • pmid:24228873
  • scopus:84882600316
ISSN
0006-2979
DOI
10.1134/S0006297913080014
language
English
LU publication?
no
additional info
Funding Information: Research in the P. Kamenski lab was supported by funding from the International Associated Laboratory “RNA mitocure”, the Russian Foundation for Basic Research, and the Russian Ministry of Education and Science (contract 8817); in the V. Hauryliuk lab by Estonian Science Foundation grants (ETF9012 and PUT37) and European Regional Development Fund (RLOTITIPP), and in the N. Zenkin lab by the UK Biotechnology and Biosciences Research Council and by European Research Council (ERC 2007 StG 202994 MTP). A. Kuzmenko is supported by the Archimedes Foundation and by the “U.M.N.I.K” program. G. C. Atkinson is supported by Estonian Science Foundation grant ETF9020 and European Social Fund grant “Mobilitas” MJD99. Copyright: Copyright 2013 Elsevier B.V., All rights reserved.
id
ad5437e4-c72e-4eda-8173-881e2eaddaf8
date added to LUP
2021-09-24 20:46:54
date last changed
2024-01-20 13:22:43
@article{ad5437e4-c72e-4eda-8173-881e2eaddaf8,
  abstract     = {{<p>Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great detail. However, significantly less is known about translation in eukaryotic mitochondria, which is characterized by a number of unusual features. In this review, we summarize current knowledge about mitochondrial translation in different organisms while paying special attention to the aspects of this process that differ from cytoplasmic protein biosynthesis.</p>}},
  author       = {{Kuzmenko, A. V. and Levitskii, S. A. and Vinogradova, E. N. and Atkinson, G. C. and Hauryliuk, V. and Zenkin, N. and Kamenski, P. A.}},
  issn         = {{0006-2979}},
  keywords     = {{mitochondria; ribosomes; translation; translation factors}},
  language     = {{eng}},
  number       = {{8}},
  pages        = {{855--866}},
  publisher    = {{Pleiades Publishing}},
  series       = {{Biochemistry (Moscow)}},
  title        = {{Protein biosynthesis in mitochondria}},
  url          = {{http://dx.doi.org/10.1134/S0006297913080014}},
  doi          = {{10.1134/S0006297913080014}},
  volume       = {{78}},
  year         = {{2013}},
}