Protein biosynthesis in mitochondria
(2013) In Biochemistry (Moscow) 78(8). p.855-866- Abstract
Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great detail. However, significantly less is known about translation in eukaryotic mitochondria, which is characterized by a number of unusual features. In this review, we summarize current knowledge about mitochondrial translation in different organisms while paying special attention to the aspects of this process that differ from cytoplasmic protein biosynthesis.
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https://lup.lub.lu.se/record/ad5437e4-c72e-4eda-8173-881e2eaddaf8
- author
- Kuzmenko, A. V. ; Levitskii, S. A. ; Vinogradova, E. N. ; Atkinson, G. C. LU ; Hauryliuk, V. LU ; Zenkin, N. and Kamenski, P. A.
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- keywords
- mitochondria, ribosomes, translation, translation factors
- in
- Biochemistry (Moscow)
- volume
- 78
- issue
- 8
- pages
- 855 - 866
- publisher
- Pleiades Publishing
- external identifiers
-
- pmid:24228873
- scopus:84882600316
- ISSN
- 0006-2979
- DOI
- 10.1134/S0006297913080014
- language
- English
- LU publication?
- no
- additional info
- Funding Information: Research in the P. Kamenski lab was supported by funding from the International Associated Laboratory “RNA mitocure”, the Russian Foundation for Basic Research, and the Russian Ministry of Education and Science (contract 8817); in the V. Hauryliuk lab by Estonian Science Foundation grants (ETF9012 and PUT37) and European Regional Development Fund (RLOTITIPP), and in the N. Zenkin lab by the UK Biotechnology and Biosciences Research Council and by European Research Council (ERC 2007 StG 202994 MTP). A. Kuzmenko is supported by the Archimedes Foundation and by the “U.M.N.I.K” program. G. C. Atkinson is supported by Estonian Science Foundation grant ETF9020 and European Social Fund grant “Mobilitas” MJD99. Copyright: Copyright 2013 Elsevier B.V., All rights reserved.
- id
- ad5437e4-c72e-4eda-8173-881e2eaddaf8
- date added to LUP
- 2021-09-24 20:46:54
- date last changed
- 2024-01-20 13:22:43
@article{ad5437e4-c72e-4eda-8173-881e2eaddaf8, abstract = {{<p>Translation, that is biosynthesis of polypeptides in accordance with information encoded in the genome, is one of the most important processes in the living cell, and it has been in the spotlight of international research for many years. The mechanisms of protein biosynthesis in bacteria and in the eukaryotic cytoplasm are now understood in great detail. However, significantly less is known about translation in eukaryotic mitochondria, which is characterized by a number of unusual features. In this review, we summarize current knowledge about mitochondrial translation in different organisms while paying special attention to the aspects of this process that differ from cytoplasmic protein biosynthesis.</p>}}, author = {{Kuzmenko, A. V. and Levitskii, S. A. and Vinogradova, E. N. and Atkinson, G. C. and Hauryliuk, V. and Zenkin, N. and Kamenski, P. A.}}, issn = {{0006-2979}}, keywords = {{mitochondria; ribosomes; translation; translation factors}}, language = {{eng}}, number = {{8}}, pages = {{855--866}}, publisher = {{Pleiades Publishing}}, series = {{Biochemistry (Moscow)}}, title = {{Protein biosynthesis in mitochondria}}, url = {{http://dx.doi.org/10.1134/S0006297913080014}}, doi = {{10.1134/S0006297913080014}}, volume = {{78}}, year = {{2013}}, }