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Quality of life and mild cognitive impairment in early Parkinson's disease : does subtype matter?

Lawson, Rachael A; Yarnall, Alison J; Duncan, Gordon W; Khoo, Tien K; Breen, David P; Barker, Roger A LU ; Collerton, Daniel; Taylor, John-Paul and Burn, David J (2014) In Journal of Parkinson's Disease 4(3). p.6-331
Abstract

We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than... (More)

We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p > 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.

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Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
keywords
Aged, Cohort Studies, Female, Humans, Male, Middle Aged, Mild Cognitive Impairment, Neuropsychological Tests, Parkinson Disease, Quality of Life, Journal Article, Research Support, Non-U.S. Gov't
in
Journal of Parkinson's Disease
volume
4
issue
3
pages
6 pages
publisher
IOS Press
external identifiers
  • scopus:84964314812
ISSN
1877-718X
DOI
10.3233/JPD-140390
language
English
LU publication?
no
id
ad9fb23a-1ac3-490c-8d78-eeaa52f34cd7
date added to LUP
2016-11-24 15:12:21
date last changed
2017-10-22 05:22:29
@article{ad9fb23a-1ac3-490c-8d78-eeaa52f34cd7,
  abstract     = {<p>We evaluated the association between mild cognitive impairment (MCI) subtypes and quality of life (QoL) in 219 newly diagnosed Parkinson's disease (PD) patients without dementia. Participants completed neuropsychological tests of attention, executive function, visuospatial function, memory, and language, and reported QoL using the Parkinson's Disease Questionnaire. Impairments were most common in executive function, memory and attention. MCI subtypes were classified according to Movement Disorder Society Task Force criteria. More severe cognitive impairment was associated with poorer quality of life (p = 0.01), but subtype of impairment was not (p &gt; 0.10), suggesting that the nature of cognitive impairment is less significant than its severity.</p>},
  author       = {Lawson, Rachael A and Yarnall, Alison J and Duncan, Gordon W and Khoo, Tien K and Breen, David P and Barker, Roger A and Collerton, Daniel and Taylor, John-Paul and Burn, David J},
  issn         = {1877-718X},
  keyword      = {Aged,Cohort Studies,Female,Humans,Male,Middle Aged,Mild Cognitive Impairment,Neuropsychological Tests,Parkinson Disease,Quality of Life,Journal Article,Research Support, Non-U.S. Gov't},
  language     = {eng},
  number       = {3},
  pages        = {6--331},
  publisher    = {IOS Press},
  series       = {Journal of Parkinson's Disease},
  title        = {Quality of life and mild cognitive impairment in early Parkinson's disease : does subtype matter?},
  url          = {http://dx.doi.org/10.3233/JPD-140390},
  volume       = {4},
  year         = {2014},
}