The growth of exocrine pancreatic insufficient young pigs fed an elemental diet is dependent on enteral pancreatin supplementation
(2010) 11th International Symposium on Digestive Physiology of Pigs 134(1-3). p.50-52- Abstract
- Young exocrine pancreas insufficient (EPI) pigs given a commercial feed (polymeric diet) show growth retardation that can be reversed by dietary supplementation with pancreatic enzymes. Our aim was to investigate if providing an elemental diet, mimicking a pre-digested diet, can support body growth in EPI-pigs. Thus, EPI-pigs, pancreatic duct-ligated at 12.2 +/- 2.6 weeks of age (15.3 +/- 4.8 kg), were fed for 6 days either a commercial polymeric pig feed or infused i.v. with an elemental diet, with or without oral supplementation with a porcine enzyme preparation (Creon (R)). The body weight (BW) gain was then compared at day 7. Control pigs (with intact pancreata) showed a 14.0 +/- 1.3% increase in BW independent of the diet, while... (More)
- Young exocrine pancreas insufficient (EPI) pigs given a commercial feed (polymeric diet) show growth retardation that can be reversed by dietary supplementation with pancreatic enzymes. Our aim was to investigate if providing an elemental diet, mimicking a pre-digested diet, can support body growth in EPI-pigs. Thus, EPI-pigs, pancreatic duct-ligated at 12.2 +/- 2.6 weeks of age (15.3 +/- 4.8 kg), were fed for 6 days either a commercial polymeric pig feed or infused i.v. with an elemental diet, with or without oral supplementation with a porcine enzyme preparation (Creon (R)). The body weight (BW) gain was then compared at day 7. Control pigs (with intact pancreata) showed a 14.0 +/- 1.3% increase in BW independent of the diet, while EPI-pigs given the same diets either lost (polymeric diet) or slightly increased (elemental diet) their BW. In contrast, EPI-pigs fed the polymeric feed with Creon supplementation showed a normalised growth and EPI-pigs given the elemental diet with Creon supplementation gained 8.5 +/- 0.7% in BW. In conclusion, control pigs maintained a normal growth, independently of the diet being given in polymeric or elemental form, while EPI-pigs showed an impaired growth when receiving the same diets without oral enzyme supplementation. This suggests that pancreatic juice or enzyme preparations, in addition to their digestive properties, stimulate nutrient assimilation and anabolic processes in young fast-growing pigs. (C) 2010 Elsevier B.V. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1753111
- author
- Rengman, Sofia LU ; Fedkiv, Olexandr LU ; Botermans, Jos ; Svendsen, Jorgen ; Weström, Björn LU and Pierzynowski, Stefan LU
- organization
- publishing date
- 2010
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- keywords
- Elemental diet, Pancreatic enzymes, Pancreatic duct ligation, Polymeric, diet
- host publication
- Livestock Science
- volume
- 134
- issue
- 1-3
- pages
- 50 - 52
- publisher
- Elsevier
- conference name
- 11th International Symposium on Digestive Physiology of Pigs
- conference location
- Costa Daurada, Spain
- conference dates
- 2009-05-20 - 2009-05-22
- external identifiers
-
- wos:000284025800015
- scopus:77957135955
- ISSN
- 1871-1413
- DOI
- 10.1016/j.livsci.2010.06.094
- language
- English
- LU publication?
- yes
- id
- af64c9f2-32e0-4222-9756-6faaba11bca9 (old id 1753111)
- date added to LUP
- 2016-04-01 13:28:49
- date last changed
- 2022-01-27 19:25:24
@inproceedings{af64c9f2-32e0-4222-9756-6faaba11bca9,
abstract = {{Young exocrine pancreas insufficient (EPI) pigs given a commercial feed (polymeric diet) show growth retardation that can be reversed by dietary supplementation with pancreatic enzymes. Our aim was to investigate if providing an elemental diet, mimicking a pre-digested diet, can support body growth in EPI-pigs. Thus, EPI-pigs, pancreatic duct-ligated at 12.2 +/- 2.6 weeks of age (15.3 +/- 4.8 kg), were fed for 6 days either a commercial polymeric pig feed or infused i.v. with an elemental diet, with or without oral supplementation with a porcine enzyme preparation (Creon (R)). The body weight (BW) gain was then compared at day 7. Control pigs (with intact pancreata) showed a 14.0 +/- 1.3% increase in BW independent of the diet, while EPI-pigs given the same diets either lost (polymeric diet) or slightly increased (elemental diet) their BW. In contrast, EPI-pigs fed the polymeric feed with Creon supplementation showed a normalised growth and EPI-pigs given the elemental diet with Creon supplementation gained 8.5 +/- 0.7% in BW. In conclusion, control pigs maintained a normal growth, independently of the diet being given in polymeric or elemental form, while EPI-pigs showed an impaired growth when receiving the same diets without oral enzyme supplementation. This suggests that pancreatic juice or enzyme preparations, in addition to their digestive properties, stimulate nutrient assimilation and anabolic processes in young fast-growing pigs. (C) 2010 Elsevier B.V. All rights reserved.}},
author = {{Rengman, Sofia and Fedkiv, Olexandr and Botermans, Jos and Svendsen, Jorgen and Weström, Björn and Pierzynowski, Stefan}},
booktitle = {{Livestock Science}},
issn = {{1871-1413}},
keywords = {{Elemental diet; Pancreatic enzymes; Pancreatic duct ligation; Polymeric; diet}},
language = {{eng}},
number = {{1-3}},
pages = {{50--52}},
publisher = {{Elsevier}},
title = {{The growth of exocrine pancreatic insufficient young pigs fed an elemental diet is dependent on enteral pancreatin supplementation}},
url = {{http://dx.doi.org/10.1016/j.livsci.2010.06.094}},
doi = {{10.1016/j.livsci.2010.06.094}},
volume = {{134}},
year = {{2010}},
}