Hydration for health hypothesis : a narrative review of supporting evidence
(2021) In European Journal of Nutrition 60(3). p.1167-1180- Abstract
Purpose: An increasing body of evidence suggests that excreting a generous volume of diluted urine is associated with short- and long-term beneficial health effects, especially for kidney and metabolic function. However, water intake and hydration remain under-investigated and optimal hydration is poorly and inconsistently defined. This review tests the hypothesis that optimal chronic water intake positively impacts various aspects of health and proposes an evidence-based definition of optimal hydration. Methods: Search strategy included PubMed and Google Scholar using relevant keywords for each health outcome, complemented by manual search of article reference lists and the expertise of relevant practitioners for each area studied.... (More)
Purpose: An increasing body of evidence suggests that excreting a generous volume of diluted urine is associated with short- and long-term beneficial health effects, especially for kidney and metabolic function. However, water intake and hydration remain under-investigated and optimal hydration is poorly and inconsistently defined. This review tests the hypothesis that optimal chronic water intake positively impacts various aspects of health and proposes an evidence-based definition of optimal hydration. Methods: Search strategy included PubMed and Google Scholar using relevant keywords for each health outcome, complemented by manual search of article reference lists and the expertise of relevant practitioners for each area studied. Results: The available literature suggest the effects of increased water intake on health may be direct, due to increased urine flow or urine dilution, or indirect, mediated by a reduction in osmotically -stimulated vasopressin (AVP). Urine flow affects the formation of kidney stones and recurrence of urinary tract infection, while increased circulating AVP is implicated in metabolic disease, chronic kidney disease, and autosomal dominant polycystic kidney disease. Conclusion: In order to ensure optimal hydration, it is proposed that optimal total water intake should approach 2.5 to 3.5 L day−1 to allow for the daily excretion of 2 to 3 L of dilute (< 500 mOsm kg−1) urine. Simple urinary markers of hydration such as urine color or void frequency may be used to monitor and adjust intake.
(Less)
- author
- Perrier, Erica T.
; Armstrong, Lawrence E.
; Bottin, Jeanne H.
; Clark, William F.
; Dolci, Alberto
; Guelinckx, Isabelle
; Iroz, Alison
; Kavouras, Stavros A.
; Lang, Florian
; Lieberman, Harris R.
; Melander, Olle
LU
; Morin, Clementine
; Seksek, Isabelle
; Stookey, Jodi D.
; Tack, Ivan
; Vanhaecke, Tiphaine
; Vecchio, Mariacristina
and Péronnet, François
(Less) - organization
- publishing date
- 2021
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Arginine vasopressin, Copeptin, Metabolic, Renal, Water
- in
- European Journal of Nutrition
- volume
- 60
- issue
- 3
- pages
- 1167 - 1180
- publisher
- Springer
- external identifiers
-
- scopus:85087569799
- pmid:32632658
- ISSN
- 1436-6207
- DOI
- 10.1007/s00394-020-02296-z
- language
- English
- LU publication?
- yes
- id
- afc1d5b9-0c21-4597-b039-c41fb0414ad4
- date added to LUP
- 2020-07-17 14:38:58
- date last changed
- 2024-06-13 20:05:29
@article{afc1d5b9-0c21-4597-b039-c41fb0414ad4,
abstract = {{<p>Purpose: An increasing body of evidence suggests that excreting a generous volume of diluted urine is associated with short- and long-term beneficial health effects, especially for kidney and metabolic function. However, water intake and hydration remain under-investigated and optimal hydration is poorly and inconsistently defined. This review tests the hypothesis that optimal chronic water intake positively impacts various aspects of health and proposes an evidence-based definition of optimal hydration. Methods: Search strategy included PubMed and Google Scholar using relevant keywords for each health outcome, complemented by manual search of article reference lists and the expertise of relevant practitioners for each area studied. Results: The available literature suggest the effects of increased water intake on health may be direct, due to increased urine flow or urine dilution, or indirect, mediated by a reduction in osmotically -stimulated vasopressin (AVP). Urine flow affects the formation of kidney stones and recurrence of urinary tract infection, while increased circulating AVP is implicated in metabolic disease, chronic kidney disease, and autosomal dominant polycystic kidney disease. Conclusion: In order to ensure optimal hydration, it is proposed that optimal total water intake should approach 2.5 to 3.5 L day<sup>−1</sup> to allow for the daily excretion of 2 to 3 L of dilute (< 500 mOsm kg<sup>−1</sup>) urine. Simple urinary markers of hydration such as urine color or void frequency may be used to monitor and adjust intake.</p>}},
author = {{Perrier, Erica T. and Armstrong, Lawrence E. and Bottin, Jeanne H. and Clark, William F. and Dolci, Alberto and Guelinckx, Isabelle and Iroz, Alison and Kavouras, Stavros A. and Lang, Florian and Lieberman, Harris R. and Melander, Olle and Morin, Clementine and Seksek, Isabelle and Stookey, Jodi D. and Tack, Ivan and Vanhaecke, Tiphaine and Vecchio, Mariacristina and Péronnet, François}},
issn = {{1436-6207}},
keywords = {{Arginine vasopressin; Copeptin; Metabolic; Renal; Water}},
language = {{eng}},
number = {{3}},
pages = {{1167--1180}},
publisher = {{Springer}},
series = {{European Journal of Nutrition}},
title = {{Hydration for health hypothesis : a narrative review of supporting evidence}},
url = {{http://dx.doi.org/10.1007/s00394-020-02296-z}},
doi = {{10.1007/s00394-020-02296-z}},
volume = {{60}},
year = {{2021}},
}