Advanced

Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions

Epp, Alexandra; Hobusch, Juliane; Bartsch, Yannic C; Petry, Janina; Lilienthal, Gina-Maria; Koeleman, Carolien A M; Eschweiler, Simon; Möbs, Christian; Hall, Ashley and Morris, Suzanne C, et al. (2017) In Journal of Allergy and Clinical Immunology
Abstract

In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.

Please use this url to cite or link to this publication:
@article{afe410db-1a2e-4c62-b66b-70e84814a4eb,
  abstract     = {<p>In presence of high allergen dosis besides IgE also IgG antibodies can induce allergic reactions, whose severity is dependent on the induced type of IgG Fc glycosylation, what should be considered for new AIT protocols containing new adjuvants.</p>},
  author       = {Epp, Alexandra and Hobusch, Juliane and Bartsch, Yannic C and Petry, Janina and Lilienthal, Gina-Maria and Koeleman, Carolien A M and Eschweiler, Simon and Möbs, Christian and Hall, Ashley and Morris, Suzanne C and Braumann, Dominique and Engellenner, Christine and Bitterling, Josephine and Rahmöller, Johann and Leliavski, Alexei and Thurmann, Robina and Collin, Mattias and Moremen, Kelley W and Strait, Richard T and Blanchard, Véronique and Petersen, Arnd and Gemoll, Timo and Habermann, Jens K and Petersen, Frank and Nandy, Andreas and Kahlert, Helga and Hertl, Michael and Wuhrer, Manfred and Pfützner, Wolfgang and Jappe, Uta and Finkelman, Fred D and Ehlers, Marc},
  issn         = {1097-6825},
  language     = {eng},
  month        = {07},
  publisher    = {Elsevier},
  series       = {Journal of Allergy and Clinical Immunology},
  title        = {Sialylation of IgG antibodies inhibits IgG-mediated allergic reactions},
  url          = {http://dx.doi.org/10.1016/j.jaci.2017.06.021},
  year         = {2017},
}