Co-Infection with 'Candidatus Neoehrlichia mikurensis' and Borrelia afzelii in Ixodes ricinus Ticks in Southern Sweden.
(2013) In Vector Borne and Zoonotic Diseases 13(7). p.438-442- Abstract
- Abstract The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen in Europe and appears to be the second most common pathogenic bacterium in Ixodes ricinus ticks in central Europe, second to Borrelia afzelii. Here, we investigate the prevalence of 'Candidatus N. mikurensis' in host-seeking ticks in southern Sweden and the rate of co-infection with B. afzelii. We developed a real-time qPCR assay targeting the groEL gene of 'Candidatus N. mikurensis' and applied this assay to 949 I. ricinus ticks collected at several locations over 2 years. We found an overall prevalence of 6.0%, which means that Candidatus N. mikurensis is one of the most common tick-transmitted zoonotic agents in this... (More)
- Abstract The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen in Europe and appears to be the second most common pathogenic bacterium in Ixodes ricinus ticks in central Europe, second to Borrelia afzelii. Here, we investigate the prevalence of 'Candidatus N. mikurensis' in host-seeking ticks in southern Sweden and the rate of co-infection with B. afzelii. We developed a real-time qPCR assay targeting the groEL gene of 'Candidatus N. mikurensis' and applied this assay to 949 I. ricinus ticks collected at several locations over 2 years. We found an overall prevalence of 6.0%, which means that Candidatus N. mikurensis is one of the most common tick-transmitted zoonotic agents in this area. Co-infections with both 'Candidatus N. mikurensis' and B. afzelii occurred in 2.1% of the ticks, which is significantly more than expected under random co-occurrence. The infection intensity (number of bacterial cells) of 'Candidatus N. mikurensis' was not affected by co-infection with B. afzelii, and vice versa. We conclude that there is a risk for simultaneous transmission of these 2 tick-borne pathogens. The potential medical consequences of this require further investigation. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/3733726
- author
- Andersson, Martin LU ; Bartkova, Simona ; Lindestad, Olle and Råberg, Lars
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Vector Borne and Zoonotic Diseases
- volume
- 13
- issue
- 7
- pages
- 438 - 442
- publisher
- Mary Ann Liebert, Inc.
- external identifiers
-
- wos:000321244700002
- pmid:23590321
- scopus:84879974523
- pmid:23590321
- ISSN
- 1557-7759
- DOI
- 10.1089/vbz.2012.1118
- project
- Borrelia in rodents
- language
- English
- LU publication?
- yes
- id
- b037bf50-6f98-4c8d-9ae6-59f3c5bb0ab9 (old id 3733726)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/23590321?dopt=Abstract
- date added to LUP
- 2016-04-01 10:42:15
- date last changed
- 2022-04-20 05:24:12
@article{b037bf50-6f98-4c8d-9ae6-59f3c5bb0ab9,
abstract = {{Abstract The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen in Europe and appears to be the second most common pathogenic bacterium in Ixodes ricinus ticks in central Europe, second to Borrelia afzelii. Here, we investigate the prevalence of 'Candidatus N. mikurensis' in host-seeking ticks in southern Sweden and the rate of co-infection with B. afzelii. We developed a real-time qPCR assay targeting the groEL gene of 'Candidatus N. mikurensis' and applied this assay to 949 I. ricinus ticks collected at several locations over 2 years. We found an overall prevalence of 6.0%, which means that Candidatus N. mikurensis is one of the most common tick-transmitted zoonotic agents in this area. Co-infections with both 'Candidatus N. mikurensis' and B. afzelii occurred in 2.1% of the ticks, which is significantly more than expected under random co-occurrence. The infection intensity (number of bacterial cells) of 'Candidatus N. mikurensis' was not affected by co-infection with B. afzelii, and vice versa. We conclude that there is a risk for simultaneous transmission of these 2 tick-borne pathogens. The potential medical consequences of this require further investigation.}},
author = {{Andersson, Martin and Bartkova, Simona and Lindestad, Olle and Råberg, Lars}},
issn = {{1557-7759}},
language = {{eng}},
number = {{7}},
pages = {{438--442}},
publisher = {{Mary Ann Liebert, Inc.}},
series = {{Vector Borne and Zoonotic Diseases}},
title = {{Co-Infection with 'Candidatus Neoehrlichia mikurensis' and Borrelia afzelii in Ixodes ricinus Ticks in Southern Sweden.}},
url = {{http://dx.doi.org/10.1089/vbz.2012.1118}},
doi = {{10.1089/vbz.2012.1118}},
volume = {{13}},
year = {{2013}},
}