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Grafted biomembranes containing membrane proteins--the case of the leucine transporter

Jagalski, Vivien ; Barker, Robert D ; Thygesen, Mikkel B ; Gotfryd, Kamil ; Krüger, Mie B ; Shi, Lei ; Maric, Selma LU ; Bovet, Nicolas LU ; Moulin, Martine and Haertlein, Michael , et al. (2015) In Soft Matter 11(39). p.11-7707
Abstract

Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations.

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organization
publishing date
type
Contribution to journal
publication status
published
keywords
Amino Acid Transport Systems/chemistry, Detergents/chemistry, Gold/chemistry, Lipid Bilayers/chemistry, Molecular Dynamics Simulation, Nitrilotriacetic Acid/chemistry, Phosphatidylcholines/chemistry, Polyethylene Glycols/chemistry, Quartz Crystal Microbalance Techniques, Sodium/chemistry
in
Soft Matter
volume
11
issue
39
pages
5 pages
publisher
Royal Society of Chemistry
external identifiers
  • scopus:84942760683
  • pmid:26325086
ISSN
1744-6848
DOI
10.1039/c5sm01490e
language
English
LU publication?
yes
id
b099abd0-9cc8-44da-962f-7c41969ab280
date added to LUP
2018-07-19 11:58:44
date last changed
2025-01-08 12:24:59
@article{b099abd0-9cc8-44da-962f-7c41969ab280,
  abstract     = {{<p>Here, we bind the sodium dependent amino acid transporter on nitrilotriacetic acid/polyethylene glycol functionalized gold sensors in detergents and perform a detergent-lipid exchange with phosphatidylcholine. We characterize the LeuT structure in the adsorbed film by magnetic contrast neutron reflection using the predicted model from molecular dynamic simulations. </p>}},
  author       = {{Jagalski, Vivien and Barker, Robert D and Thygesen, Mikkel B and Gotfryd, Kamil and Krüger, Mie B and Shi, Lei and Maric, Selma and Bovet, Nicolas and Moulin, Martine and Haertlein, Michael and Pomorski, Thomas Günther and Loland, Claus J and Cárdenas, Marité}},
  issn         = {{1744-6848}},
  keywords     = {{Amino Acid Transport Systems/chemistry; Detergents/chemistry; Gold/chemistry; Lipid Bilayers/chemistry; Molecular Dynamics Simulation; Nitrilotriacetic Acid/chemistry; Phosphatidylcholines/chemistry; Polyethylene Glycols/chemistry; Quartz Crystal Microbalance Techniques; Sodium/chemistry}},
  language     = {{eng}},
  month        = {{10}},
  number       = {{39}},
  pages        = {{11--7707}},
  publisher    = {{Royal Society of Chemistry}},
  series       = {{Soft Matter}},
  title        = {{Grafted biomembranes containing membrane proteins--the case of the leucine transporter}},
  url          = {{http://dx.doi.org/10.1039/c5sm01490e}},
  doi          = {{10.1039/c5sm01490e}},
  volume       = {{11}},
  year         = {{2015}},
}