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On hydrophobicity correlations in protein chains

Irbäck, A LU orcid and Sandelin, E LU (2000) In Biophysical Journal 79(5). p.8-2252
Abstract

We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in significant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of real enzymes, too.

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author
and
organization
publishing date
type
Contribution to journal
publication status
published
keywords
Biophysical Phenomena, Biophysics, Enzymes, Models, Chemical, Protein Folding, Proteins
in
Biophysical Journal
volume
79
issue
5
pages
7 pages
publisher
Cell Press
external identifiers
  • scopus:0033738980
  • pmid:11053106
ISSN
0006-3495
DOI
10.1016/S0006-3495(00)76472-1
language
English
LU publication?
yes
id
b0f4891d-7754-4895-a8e2-6953bba1d5fb
date added to LUP
2016-08-17 16:28:16
date last changed
2025-01-12 09:53:48
@article{b0f4891d-7754-4895-a8e2-6953bba1d5fb,
  abstract     = {{<p>We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in significant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of real enzymes, too.</p>}},
  author       = {{Irbäck, A and Sandelin, E}},
  issn         = {{0006-3495}},
  keywords     = {{Biophysical Phenomena; Biophysics; Enzymes; Models, Chemical; Protein Folding; Proteins}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{8--2252}},
  publisher    = {{Cell Press}},
  series       = {{Biophysical Journal}},
  title        = {{On hydrophobicity correlations in protein chains}},
  url          = {{http://dx.doi.org/10.1016/S0006-3495(00)76472-1}},
  doi          = {{10.1016/S0006-3495(00)76472-1}},
  volume       = {{79}},
  year         = {{2000}},
}