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Health-related quality of life in patients with pharyngeal carcinoma: A five-year follow-up.

Nordgren, Mats LU ; Jannert, Magnus LU ; Boysen, Morten ; Ahlner-Elmqvist, Marianne LU ; Silander, Ewa ; Bjordal, Kristin and Hammerlid, Eva (2006) In Head and Neck 28(Nov 14). p.339-349
Abstract
Purpose. The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multi-center study. Methods. Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). Results. Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions... (More)
Purpose. The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multi-center study. Methods. Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). Results. Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions and teeth increased between 1 and 5 years. The HRQL at diagnosis was associated with survival. Patients with oropharyngeal carcinoma reported better HRQL than patients with hypopharyngeal carcinoma. Conclusions. For patients with pharyngeal carcinoma, the HRQL at diagnosis seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of pharyngeal carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and thick secretions. (c) 2005 Wiley Periodicals, Inc. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
pharyngeal carcinoma, longitudinal HRQL, EORTC QLQ-C30, predictive factors, EORTC, OLO-H&N35
in
Head and Neck
volume
28
issue
Nov 14
pages
339 - 349
publisher
John Wiley and Sons Inc.
external identifiers
  • wos:000236536300007
  • scopus:33645658347
ISSN
1043-3074
DOI
10.1002/hed.20334
language
English
LU publication?
yes
additional info
The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Disease of the Paranasal Sinus, Cancer and HRQL (013243520), Reconstructive Surgery (013240300)
id
b1bc6d41-e81b-4411-b0d1-57ae26fe9edc (old id 147950)
alternative location
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=16287136&dopt=Abstract
date added to LUP
2016-04-01 12:09:10
date last changed
2020-07-01 02:01:41
@article{b1bc6d41-e81b-4411-b0d1-57ae26fe9edc,
  abstract     = {Purpose. The purpose was to evaluate the health-related quality of life (HRQL) of patients with pharyngeal carcinoma at diagnosis and after 1 and 5 years in relation to tumor location and treatment modality in a prospective multi-center study. Methods. Eighty-nine patients with pharyngeal carcinoma (mean age, 60.0 years; 76% men) were evaluated using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 (EORTC QLQ-C30) and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Cancer Module (EORTC QLQ-H&N35). Results. Problems with dry mouth and teeth became worse between diagnosis and the 5-year follow-up. Problems with thick secretions and teeth increased between 1 and 5 years. The HRQL at diagnosis was associated with survival. Patients with oropharyngeal carcinoma reported better HRQL than patients with hypopharyngeal carcinoma. Conclusions. For patients with pharyngeal carcinoma, the HRQL at diagnosis seems to be an important factor for the prognosis of both HRQL over time and survival. Treatment of pharyngeal carcinoma often results in long-term side effects such as dry mouth, problems with teeth, and thick secretions. (c) 2005 Wiley Periodicals, Inc.},
  author       = {Nordgren, Mats and Jannert, Magnus and Boysen, Morten and Ahlner-Elmqvist, Marianne and Silander, Ewa and Bjordal, Kristin and Hammerlid, Eva},
  issn         = {1043-3074},
  language     = {eng},
  number       = {Nov 14},
  pages        = {339--349},
  publisher    = {John Wiley and Sons Inc.},
  series       = {Head and Neck},
  title        = {Health-related quality of life in patients with pharyngeal carcinoma: A five-year follow-up.},
  url          = {http://dx.doi.org/10.1002/hed.20334},
  doi          = {10.1002/hed.20334},
  volume       = {28},
  year         = {2006},
}