A fully automatic algorithm for assessing T2* and its certainty value for accurate cardiac and liver iron load determination
(2013) 16th Annual SCMR Scientific Sessions In Journal of Cardiovascular Magnetic Resonance 15(Suppl 1).- Abstract
- Quantification of myocardial and liver iron load has become a mainstay of guiding therapy in thalassaemia patients. However, current quantification methods are user dependent for data-point exclusion before curve fitting, and do not report the T2* certainty. Recently, an automatic inline maximum likelihood estimate (MLE) method with k-space Rician noise correction was validated against the reference standard manual truncation method. We now present a vendor-independent offline tool for fully automatic post processing and T2* quantification with certainty estimates, tested in computer simulations and patients with iron overload.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/b2562262-26a0-4e76-8a31-4c5bf34b2a13
- author
- Hedström, Erik LU ; Heiberg, Einar LU ; Greil, Gerald F and Nagel, Eike
- organization
- publishing date
- 2013-01-30
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Cardiovascular Magnetic Resonance
- volume
- 15
- issue
- Suppl 1
- article number
- P141
- publisher
- BioMed Central (BMC)
- conference name
- 16th Annual SCMR Scientific Sessions
- conference location
- San Francisco, United States
- conference dates
- 2013-01-31 - 2013-02-03
- ISSN
- 1097-6647
- DOI
- 10.1186/1532-429X-15-S1-P141
- language
- English
- LU publication?
- yes
- id
- b2562262-26a0-4e76-8a31-4c5bf34b2a13
- alternative location
- http://www.jcmr-online.com/content/15/S1/P141
- date added to LUP
- 2017-02-02 11:37:55
- date last changed
- 2018-11-21 21:29:25
@article{b2562262-26a0-4e76-8a31-4c5bf34b2a13, abstract = {{Quantification of myocardial and liver iron load has become a mainstay of guiding therapy in thalassaemia patients. However, current quantification methods are user dependent for data-point exclusion before curve fitting, and do not report the T2* certainty. Recently, an automatic inline maximum likelihood estimate (MLE) method with k-space Rician noise correction was validated against the reference standard manual truncation method. We now present a vendor-independent offline tool for fully automatic post processing and T2* quantification with certainty estimates, tested in computer simulations and patients with iron overload.}}, author = {{Hedström, Erik and Heiberg, Einar and Greil, Gerald F and Nagel, Eike}}, issn = {{1097-6647}}, language = {{eng}}, month = {{01}}, number = {{Suppl 1}}, publisher = {{BioMed Central (BMC)}}, series = {{Journal of Cardiovascular Magnetic Resonance}}, title = {{A fully automatic algorithm for assessing T2* and its certainty value for accurate cardiac and liver iron load determination}}, url = {{http://dx.doi.org/10.1186/1532-429X-15-S1-P141}}, doi = {{10.1186/1532-429X-15-S1-P141}}, volume = {{15}}, year = {{2013}}, }