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Advancing personalised care in atrial fibrillation and stroke : The potential impact of AI from prevention to rehabilitation

Ortega-Martorell, Sandra LU ; Olier, Ivan ; Ohlsson, Mattias LU orcid and Lip, Gregory Y.H. (2024) In Trends in Cardiovascular Medicine
Abstract

Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers expected to rise due to ageing and improved survival rates. Functional recovery from AF-related stroke is often unsatisfactory, leading to prolonged hospital stays, severe disability, and high mortality. Despite advances in AF and stroke research, the full pathophysiological and management issues between AF and stroke increasingly need... (More)

Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers expected to rise due to ageing and improved survival rates. Functional recovery from AF-related stroke is often unsatisfactory, leading to prolonged hospital stays, severe disability, and high mortality. Despite advances in AF and stroke research, the full pathophysiological and management issues between AF and stroke increasingly need innovative approaches such as artificial intelligence (AI) and machine learning (ML). Current risk assessment tools focus on static risk factors, neglecting the dynamic nature of risk influenced by acute illness, ageing, and comorbidities. Incorporating biomarkers and automated ECG analysis could enhance pathophysiological understanding. This paper highlights the need for personalised, integrative approaches in AF and stroke management, emphasising the potential of AI and ML to improve risk prediction, treatment personalisation, and rehabilitation outcomes. Further research is essential to optimise care and reduce the burden of AF and stroke on patients and healthcare systems.

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publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Artificial Intelligence, Atrial Fibrillation, Burden, Digital Twins, Impact, Machine Learning, Personalised care, Significance, Stroke
in
Trends in Cardiovascular Medicine
publisher
Elsevier
external identifiers
  • pmid:39653093
  • scopus:85211967182
ISSN
1050-1738
DOI
10.1016/j.tcm.2024.12.003
language
English
LU publication?
yes
id
b3893531-76d7-48c1-83ba-83c4ecaf74b3
date added to LUP
2025-01-30 11:21:05
date last changed
2025-07-04 11:07:20
@article{b3893531-76d7-48c1-83ba-83c4ecaf74b3,
  abstract     = {{<p>Atrial fibrillation (AF) is a complex condition caused by various underlying pathophysiological disorders and is the most common heart arrhythmia worldwide, affecting 2 % of the European population. This prevalence increases with age, imposing significant financial, economic, and human burdens. In Europe, stroke is the second leading cause of death and the primary cause of disability, with numbers expected to rise due to ageing and improved survival rates. Functional recovery from AF-related stroke is often unsatisfactory, leading to prolonged hospital stays, severe disability, and high mortality. Despite advances in AF and stroke research, the full pathophysiological and management issues between AF and stroke increasingly need innovative approaches such as artificial intelligence (AI) and machine learning (ML). Current risk assessment tools focus on static risk factors, neglecting the dynamic nature of risk influenced by acute illness, ageing, and comorbidities. Incorporating biomarkers and automated ECG analysis could enhance pathophysiological understanding. This paper highlights the need for personalised, integrative approaches in AF and stroke management, emphasising the potential of AI and ML to improve risk prediction, treatment personalisation, and rehabilitation outcomes. Further research is essential to optimise care and reduce the burden of AF and stroke on patients and healthcare systems.</p>}},
  author       = {{Ortega-Martorell, Sandra and Olier, Ivan and Ohlsson, Mattias and Lip, Gregory Y.H.}},
  issn         = {{1050-1738}},
  keywords     = {{Artificial Intelligence; Atrial Fibrillation; Burden; Digital Twins; Impact; Machine Learning; Personalised care; Significance; Stroke}},
  language     = {{eng}},
  publisher    = {{Elsevier}},
  series       = {{Trends in Cardiovascular Medicine}},
  title        = {{Advancing personalised care in atrial fibrillation and stroke : The potential impact of AI from prevention to rehabilitation}},
  url          = {{http://dx.doi.org/10.1016/j.tcm.2024.12.003}},
  doi          = {{10.1016/j.tcm.2024.12.003}},
  year         = {{2024}},
}