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Burden of malignant mesothelioma in China during 1990-2019 and the projections through 2029

Huang, Qiulin ; Chen, Youli ; Lian, Liyou ; Lei, Qiqi ; Chen, Jinfei ; Wu, Licun ; Hemminki, Kari LU ; Ji, Jianguang LU orcid and Chen, Tianhui LU (2024) In Journal of the National Cancer Center
Abstract
Objective

To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.
Methods

Data on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DALYs) associated with MM among different age groups. Temporal trends during 1990-2019 were analyzed by the Joinpoint regression models using 95% confidence interval (CI), while the projections through 2029 were calculated by Bayesian age-period-cohort model. Data on the production and consumption of asbestos in China were... (More)
Objective

To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.
Methods

Data on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DALYs) associated with MM among different age groups. Temporal trends during 1990-2019 were analyzed by the Joinpoint regression models using 95% confidence interval (CI), while the projections through 2029 were calculated by Bayesian age-period-cohort model. Data on the production and consumption of asbestos in China were obtained from the United States Geological Survey on Mineral Commodity Summaries during 1996-2023.
Results

We observed a significant elevation in incident new cases and deaths over last 3 decades, increasing from 1193 in 1990 to 2815 in 2019 for incident cases and from 1134 in 1990 to 2773 in 2019 for death cases. We found roughly 6% increase in the proportion of incident cases for those aged > 70 years (30% in 2019 versus 24% in 1990), while for the proportion of deaths similar elevation for those aged > 70 years was also found. Additionally, men had significantly higher DALYs due to MM across age groups compared to women. Asbestos consumption in China dramatically dropped since 2012 and reached bottom in 2017 with 230 kilotons. By 2029, the projected age-standardized rate for incidence and mortality is expected to reach 1.2 per million for both.
Conclusion

We found, for the first time using GBD data on the Chinese population, that the burden of MM has been significantly increasing in China over the last three decades and will continue to increase in the upcoming decade, suggesting an urgent need for a complete ban on chrysotile asbestos in China. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Malignant mesothelioma, Cancer burden, China, Global Burden of Disease (GBD) 2019
in
Journal of the National Cancer Center
pages
44 pages
publisher
Elsevier
ISSN
2667-0054
DOI
10.1016/j.jncc.2024.05.003
language
English
LU publication?
yes
id
b5111afc-abb8-4b90-af42-aed15cb88f6e
alternative location
https://linkinghub.elsevier.com/retrieve/pii/S2667005424000292
date added to LUP
2024-05-13 12:53:03
date last changed
2024-05-14 02:40:23
@article{b5111afc-abb8-4b90-af42-aed15cb88f6e,
  abstract     = {{Objective<br/><br/>To provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.<br/>Methods<br/><br/>Data on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DALYs) associated with MM among different age groups. Temporal trends during 1990-2019 were analyzed by the Joinpoint regression models using 95% confidence interval (CI), while the projections through 2029 were calculated by Bayesian age-period-cohort model. Data on the production and consumption of asbestos in China were obtained from the United States Geological Survey on Mineral Commodity Summaries during 1996-2023.<br/>Results<br/><br/>We observed a significant elevation in incident new cases and deaths over last 3 decades, increasing from 1193 in 1990 to 2815 in 2019 for incident cases and from 1134 in 1990 to 2773 in 2019 for death cases. We found roughly 6% increase in the proportion of incident cases for those aged &gt; 70 years (30% in 2019 versus 24% in 1990), while for the proportion of deaths similar elevation for those aged &gt; 70 years was also found. Additionally, men had significantly higher DALYs due to MM across age groups compared to women. Asbestos consumption in China dramatically dropped since 2012 and reached bottom in 2017 with 230 kilotons. By 2029, the projected age-standardized rate for incidence and mortality is expected to reach 1.2 per million for both.<br/>Conclusion<br/><br/>We found, for the first time using GBD data on the Chinese population, that the burden of MM has been significantly increasing in China over the last three decades and will continue to increase in the upcoming decade, suggesting an urgent need for a complete ban on chrysotile asbestos in China.}},
  author       = {{Huang, Qiulin and Chen, Youli and Lian, Liyou and Lei, Qiqi and Chen, Jinfei and Wu, Licun and Hemminki, Kari and Ji, Jianguang and Chen, Tianhui}},
  issn         = {{2667-0054}},
  keywords     = {{Malignant mesothelioma; Cancer burden; China; Global Burden of Disease (GBD) 2019}},
  language     = {{eng}},
  month        = {{05}},
  publisher    = {{Elsevier}},
  series       = {{Journal of the National Cancer Center}},
  title        = {{Burden of malignant mesothelioma in China during 1990-2019 and the projections through 2029}},
  url          = {{http://dx.doi.org/10.1016/j.jncc.2024.05.003}},
  doi          = {{10.1016/j.jncc.2024.05.003}},
  year         = {{2024}},
}