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Do negative intrusive thoughts at diagnosis predict impaired quality of life, depressed mood and waking up with anxiety 3, 12 and 24 months after radical prostatectomy?–a longitudinal study

Bock, David ; Angenete, Eva ; Asplund, Dan ; Bjartell, Anders LU ; Carlsson, Stefan ; Hugosson, Jonas ; Stinesen Kollberg, Karin ; Lantz, Anna ; Nilsson, Hanna and Prytz, Mattias , et al. (2020) In Scandinavian Journal of Urology 54(3). p.220-226
Abstract

Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12 and 24 months after surgery. Results: The group of patients with intrusive thoughts at diagnosis had a statistically significant higher postoperative prevalence of impaired quality of life, depressed mood and waking up with anxiety as compared with the group of patients with no or minor intrusive thoughts. The highest risk increase for... (More)

Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12 and 24 months after surgery. Results: The group of patients with intrusive thoughts at diagnosis had a statistically significant higher postoperative prevalence of impaired quality of life, depressed mood and waking up with anxiety as compared with the group of patients with no or minor intrusive thoughts. The highest risk increase for impaired QoL, depressed mood and waking up with anxiety ≥1/week was at 12, 3 and 3 months, respectively, where the three outcomes increased by 38% (RR: 1.38; 95%CI: 1.27–1.49)), 136% (RR: 2.36; 95%CI: 1.74–3.19)) and 165% (RR: 2.65; 95%CI: 2.22–3.17)), respectively. Conclusions: The demonstrated link between intrusive thoughts and quality of life, depressed mood and waking up with anxiety deliver is further evidence to the idea that intrusive thoughts has potential as an endpoint for assessing and predicting psychological distress among men with prostate cancer diagnosis. Trial registration number: ISRCTN06393679 (www.isrctn.com). Date of registration: 07/02/2008. Retrospectively registered.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
Intrusive thoughts, prostate cancer, quality of life
in
Scandinavian Journal of Urology
volume
54
issue
3
pages
7 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85084269368
  • pmid:32343155
ISSN
2168-1805
DOI
10.1080/21681805.2020.1754905
language
English
LU publication?
no
id
b5e704e2-e271-4e7e-ae25-56d8c231dc7d
date added to LUP
2020-05-26 10:04:21
date last changed
2024-04-17 10:46:11
@article{b5e704e2-e271-4e7e-ae25-56d8c231dc7d,
  abstract     = {{<p>Objective: To evaluate the effect of intrusive thoughts at diagnosis on quality of life, depressed mood and waking up with anxiety up to two years after radical prostatectomy. Method: The Laparoscopic Prostatectomy Robot Open (LAPPRO) trial was a prospective, longitudinal multicenter study of 4003 patients undergoing radical prostatectomy. Questionnaire data were collected preoperatively, at 3, 12 and 24 months after surgery. Results: The group of patients with intrusive thoughts at diagnosis had a statistically significant higher postoperative prevalence of impaired quality of life, depressed mood and waking up with anxiety as compared with the group of patients with no or minor intrusive thoughts. The highest risk increase for impaired QoL, depressed mood and waking up with anxiety ≥1/week was at 12, 3 and 3 months, respectively, where the three outcomes increased by 38% (RR: 1.38; 95%CI: 1.27–1.49)), 136% (RR: 2.36; 95%CI: 1.74–3.19)) and 165% (RR: 2.65; 95%CI: 2.22–3.17)), respectively. Conclusions: The demonstrated link between intrusive thoughts and quality of life, depressed mood and waking up with anxiety deliver is further evidence to the idea that intrusive thoughts has potential as an endpoint for assessing and predicting psychological distress among men with prostate cancer diagnosis. Trial registration number: ISRCTN06393679 (www.isrctn.com). Date of registration: 07/02/2008. Retrospectively registered.</p>}},
  author       = {{Bock, David and Angenete, Eva and Asplund, Dan and Bjartell, Anders and Carlsson, Stefan and Hugosson, Jonas and Stinesen Kollberg, Karin and Lantz, Anna and Nilsson, Hanna and Prytz, Mattias and Steineck, Gunnar and Thorsteinsdottir, Thordis and Wiklund, Peter and Haglind, Eva}},
  issn         = {{2168-1805}},
  keywords     = {{Intrusive thoughts; prostate cancer; quality of life}},
  language     = {{eng}},
  month        = {{04}},
  number       = {{3}},
  pages        = {{220--226}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Journal of Urology}},
  title        = {{Do negative intrusive thoughts at diagnosis predict impaired quality of life, depressed mood and waking up with anxiety 3, 12 and 24 months after radical prostatectomy?–a longitudinal study}},
  url          = {{http://dx.doi.org/10.1080/21681805.2020.1754905}},
  doi          = {{10.1080/21681805.2020.1754905}},
  volume       = {{54}},
  year         = {{2020}},
}