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What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium

Cawthon, Peggy M. ; Patel, Sheena M. ; Kritchevsky, Stephen B. ; Newman, Anne B. ; Santanasto, Adam ; Kiel, Douglas P. ; Travison, Thomas G. ; Lane, Nancy ; Cummings, Steven R. and Orwoll, Eric S. , et al. (2021) In Journals of Gerontology. Series A: Biological Sciences & Medical Sciences 76(10). p.321-327
Abstract
BACKGROUND: Cut-points to define slow walking speed have largely been derived from expert opinion. METHODS: Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not. RESULTS: Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed... (More)
BACKGROUND: Cut-points to define slow walking speed have largely been derived from expert opinion. METHODS: Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not. RESULTS: Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but (Less)
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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Classification and regression trees, Gait speed, Mobility limitation
in
Journals of Gerontology. Series A: Biological Sciences & Medical Sciences
volume
76
issue
10
pages
321 - 327
publisher
Oxford University Press
external identifiers
  • scopus:85116957011
  • pmid:34166490
ISSN
1758-535X
DOI
10.1093/gerona/glab183
language
English
LU publication?
yes
id
b6331cf1-a0d3-498b-a68b-b574c42e9a11
date added to LUP
2021-11-12 15:47:02
date last changed
2024-06-15 20:10:04
@article{b6331cf1-a0d3-498b-a68b-b574c42e9a11,
  abstract     = {{BACKGROUND: Cut-points to define slow walking speed have largely been derived from expert opinion. METHODS: Study participants (13 589 men and 5043 women aged ≥65years) had walking speed (m/s) measured over 4-6 m (mean ± SD: 1.20 ± 0.27 m/s in men and 0.94 ± 0.24 m/s in women.) Mobility limitation was defined as any self-reported difficulty with walking approximately 1/4 mile (prevalence: 12.6% men, 26.4% women). Sex-stratified classification and regression tree (CART) models with 10-fold cross-validation identified walking speed cut-points that optimally discriminated those who reported mobility limitation from those who did not. RESULTS: Among 5043 women, CART analysis identified 2 cut-points, classifying 4144 (82.2%) with walking speed ≥0.75 m/s, which we labeled as "fast"; 478 (9.5%) as "intermediate" (walking speed ≥0.62 m/s but}},
  author       = {{Cawthon, Peggy M. and Patel, Sheena M. and Kritchevsky, Stephen B. and Newman, Anne B. and Santanasto, Adam and Kiel, Douglas P. and Travison, Thomas G. and Lane, Nancy and Cummings, Steven R. and Orwoll, Eric S. and Duchowny, Kate A. and Kwok, Timothy and Hirani, Vasant and Schousboe, John and Karlsson, Magnus K. and Mellström, Dan and Ohlsson, Claes and Ljunggren, Östen and Xue, Qian Li and Shardell, Michelle and Jordan, Joanne M. and Pencina, Karol M. and Fielding, Roger A. and Magaziner, Jay and Correa-de-Araujo, Rosaly and Bhasin, Shalender and Manini, Todd M.}},
  issn         = {{1758-535X}},
  keywords     = {{Classification and regression trees; Gait speed; Mobility limitation}},
  language     = {{eng}},
  month        = {{09}},
  number       = {{10}},
  pages        = {{321--327}},
  publisher    = {{Oxford University Press}},
  series       = {{Journals of Gerontology. Series A: Biological Sciences & Medical Sciences}},
  title        = {{What Cut-Point in Gait Speed Best Discriminates Community-Dwelling Older Adults With Mobility Complaints From Those Without? A Pooled Analysis From the Sarcopenia Definitions and Outcomes Consortium}},
  url          = {{http://dx.doi.org/10.1093/gerona/glab183}},
  doi          = {{10.1093/gerona/glab183}},
  volume       = {{76}},
  year         = {{2021}},
}