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Label-free cytometry - Novel sorting parameters and opportunities

Tegenfeldt, Jonas O. LU orcid ; Beech, Jason P. LU and Holm, Stefan LU (2014) 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 p.242-245
Abstract

The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displacement (DLD) from merely a very powerful size-based sorting scheme so that it is used to sort with respect to several other physical parameters. We have explored parameters such as shape, deformability, dielectric properties, secretion and density with potential applications in bacteriology, parasitology and oncology.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Biophysics, Label free, Microfluidics, Particle sorting
host publication
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
pages
4 pages
publisher
Chemical and Biological Microsystems Society
conference name
18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
conference location
San Antonio, United States
conference dates
2014-10-26 - 2014-10-30
external identifiers
  • scopus:84941662945
ISBN
9780979806476
language
English
LU publication?
yes
id
b67d97b1-d30c-48c1-b098-d91d5e7305bc
date added to LUP
2018-10-20 08:32:57
date last changed
2021-09-22 04:29:29
@inproceedings{b67d97b1-d30c-48c1-b098-d91d5e7305bc,
  abstract     = {<p>The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displacement (DLD) from merely a very powerful size-based sorting scheme so that it is used to sort with respect to several other physical parameters. We have explored parameters such as shape, deformability, dielectric properties, secretion and density with potential applications in bacteriology, parasitology and oncology.</p>},
  author       = {Tegenfeldt, Jonas O. and Beech, Jason P. and Holm, Stefan},
  booktitle    = {18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014},
  isbn         = {9780979806476},
  language     = {eng},
  month        = {01},
  pages        = {242--245},
  publisher    = {Chemical and Biological Microsystems Society},
  title        = {Label-free cytometry - Novel sorting parameters and opportunities},
  year         = {2014},
}