Advanced

The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma

Trovik, Clement; Bauer, Henrik C F; Styring, Emelie LU ; Sundby Hall, Kirsten; Vult Von Steyern, Fredrik LU ; Eriksson, Sigvard; Johansson, Ingela; Sampo, Mika; Laitinen, Minna and Kalén, Anders, et al. (2017) In Acta Orthopaedica p.1-7
Abstract

Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining... (More)

Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results — 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation — The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers.

(Less)
Please use this url to cite or link to this publication:
author
, et al. (More)
(Less)
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Orthopaedica
pages
7 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85014579273
  • wos:000400742500018
ISSN
1745-3674
DOI
10.1080/17453674.2017.1293441
language
English
LU publication?
yes
id
b99188a5-72dc-4eec-abbe-27498ea38605
date added to LUP
2017-03-22 16:11:04
date last changed
2018-01-07 11:56:37
@article{b99188a5-72dc-4eec-abbe-27498ea38605,
  abstract     = {<p>Purpose — We wanted to examine the potential of the Scandinavian Sarcoma Group (SSG) Central Register, and evaluate referral and treatment practice for soft-tissue sarcomas in the extremities and trunk wall (STS) in the Nordic countries. Background — Based on incidence rates from the literature, 8,150 (7,000–9,300) cases of STS of the extremity and trunk wall should have been diagnosed in Norway, Finland, Iceland, and Sweden from 1987 through 2011. The SSG Register has 6,027 cases registered from this period, with 5,837 having complete registration of key variables. 10 centers have been reporting to the Register. The 5 centers that consistently report treat approximately 90% of the cases in their respective regions. The remaining centers have reported all the patients who were treated during certain time periods, but not for the entire 25-year period. Results — 59% of patients were referred to a sarcoma center untouched, i.e. before any attempt at open biopsy. There was an improvement from 52% during the first 5 years to 70% during the last 5 years. 50% had wide or better margins at surgery. Wide margins are now achieved less often than 20 years ago, in parallel with an increase in the use of radiotherapy. For the centers that consistently report, 97% of surviving patients are followed for more than 4 years. Metastasis-free survival (MFS) increased from 67% to 73% during the 25-year period. Interpretation — The Register is considered to be representative of extremity and trunk wall sarcoma disease in the population of Scandinavia, treated at the reporting centers. There were no clinically significant differences in treatment results at these centers.</p>},
  author       = {Trovik, Clement and Bauer, Henrik C F and Styring, Emelie and Sundby Hall, Kirsten and Vult Von Steyern, Fredrik and Eriksson, Sigvard and Johansson, Ingela and Sampo, Mika and Laitinen, Minna and Kalén, Anders and Jónsson, Halldór and Jebsen, Nina L and Eriksson, Mikael and Tukiainen, Erkki and Wall, Najme and Zaikova, Olga and Sigurðsson, Helgi and Lehtinen, Tuula and Bjerkehagen, Bodil and Skorpil, Mikael and Egil Eide, Geir and Johansson, Elisabeth and Alvegard, Thor A.},
  issn         = {1745-3674},
  language     = {eng},
  month        = {03},
  pages        = {1--7},
  publisher    = {Taylor & Francis},
  series       = {Acta Orthopaedica},
  title        = {The Scandinavian Sarcoma Group Central Register : 6,000 patients after 25 years of monitoring of referral and treatment of extremity and trunk wall soft-tissue sarcoma},
  url          = {http://dx.doi.org/10.1080/17453674.2017.1293441},
  year         = {2017},
}