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Moraxella catarrhalis

Verhaegh, Suzanne J.C. ; Schaar, Viveka LU ; Su, Yu Ching LU ; Riesbeck, Kristian LU orcid and Hays, John P. (2014) 3. p.1565-1586
Abstract

Moraxella catarrhalis is part of the normal bacterial flora in the nasopharynx of children, although over the past two decades, it has emerged as a significant bacterial pathogen and not simply a commensal colonizer. Moraxella catarrhalis is a common bacterial species cultured from the nasopharynx of children during otitis media episodes, with the patterns of nasopharyngeal colonization by microorganisms being important determinants for otitis media disease. Treatment of otitis media is not always appropriate, and the long-term overuse of antibiotics in otitis media reduces the effectiveness of treatment and places children at an increased risk of antibiotic-resistant infections. Because there is currently no ideal treatment for otitis... (More)

Moraxella catarrhalis is part of the normal bacterial flora in the nasopharynx of children, although over the past two decades, it has emerged as a significant bacterial pathogen and not simply a commensal colonizer. Moraxella catarrhalis is a common bacterial species cultured from the nasopharynx of children during otitis media episodes, with the patterns of nasopharyngeal colonization by microorganisms being important determinants for otitis media disease. Treatment of otitis media is not always appropriate, and the long-term overuse of antibiotics in otitis media reduces the effectiveness of treatment and places children at an increased risk of antibiotic-resistant infections. Because there is currently no ideal treatment for otitis media, an alternative to the use of antibiotics is vaccination. To date, several Moraxella catarrhalis vaccine candidates have been described, which may be effective in reducing the burden of otitis media disease.

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Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Children, Colonizer, Moraxella catarrhalis, Pathogen, Vaccine
host publication
Molecular Medical Microbiology : Second Edition - Second Edition
volume
3
pages
1565 - 1586
publisher
Elsevier
external identifiers
  • scopus:84961182627
ISBN
9780123971692
9780126775303
DOI
10.1016/B978-0-12-397169-2.00088-3
language
English
LU publication?
yes
id
bc129ba0-2d42-421b-932d-4cb0838a1388
date added to LUP
2019-06-07 15:07:33
date last changed
2021-11-10 11:38:09
@inbook{bc129ba0-2d42-421b-932d-4cb0838a1388,
  abstract     = {<p>Moraxella catarrhalis is part of the normal bacterial flora in the nasopharynx of children, although over the past two decades, it has emerged as a significant bacterial pathogen and not simply a commensal colonizer. Moraxella catarrhalis is a common bacterial species cultured from the nasopharynx of children during otitis media episodes, with the patterns of nasopharyngeal colonization by microorganisms being important determinants for otitis media disease. Treatment of otitis media is not always appropriate, and the long-term overuse of antibiotics in otitis media reduces the effectiveness of treatment and places children at an increased risk of antibiotic-resistant infections. Because there is currently no ideal treatment for otitis media, an alternative to the use of antibiotics is vaccination. To date, several Moraxella catarrhalis vaccine candidates have been described, which may be effective in reducing the burden of otitis media disease.</p>},
  author       = {Verhaegh, Suzanne J.C. and Schaar, Viveka and Su, Yu Ching and Riesbeck, Kristian and Hays, John P.},
  booktitle    = {Molecular Medical Microbiology : Second Edition},
  isbn         = {9780123971692},
  language     = {eng},
  month        = {11},
  pages        = {1565--1586},
  publisher    = {Elsevier},
  title        = {Moraxella catarrhalis},
  url          = {http://dx.doi.org/10.1016/B978-0-12-397169-2.00088-3},
  doi          = {10.1016/B978-0-12-397169-2.00088-3},
  volume       = {3},
  year         = {2014},
}