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Accessible and reliable neurometric testing in humans using a smartphone platform

Boele, H J LU ; Jung, C ; Sherry, S ; Roggeveen, L E M ; Dijkhuizen, S ; Öhman, J LU ; Abraham, E ; Uvarov, A ; Boele, C P and Gultig, K , et al. (2023) In Scientific Reports 13(1).
Abstract

Tests of human brain circuit function typically require fixed equipment in lab environments. We have developed a smartphone-based platform for neurometric testing. This platform, which uses AI models like computer vision, is optimized for at-home use and produces reproducible, robust results on a battery of tests, including eyeblink conditioning, prepulse inhibition of acoustic startle response, and startle habituation. This approach provides a scalable, universal resource for quantitative assays of central nervous system function.

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organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Humans, Reflex, Startle/physiology, Smartphone, Acoustic Stimulation, Prepulse Inhibition, Habituation, Psychophysiologic
in
Scientific Reports
volume
13
issue
1
article number
22871
publisher
Nature Publishing Group
external identifiers
  • scopus:85180196381
  • pmid:38129487
ISSN
2045-2322
DOI
10.1038/s41598-023-49568-2
language
English
LU publication?
yes
id
bc63e0ec-24e3-4294-98ff-5a6c027d522b
date added to LUP
2023-12-26 16:59:14
date last changed
2024-04-17 09:12:31
@article{bc63e0ec-24e3-4294-98ff-5a6c027d522b,
  abstract     = {{<p>Tests of human brain circuit function typically require fixed equipment in lab environments. We have developed a smartphone-based platform for neurometric testing. This platform, which uses AI models like computer vision, is optimized for at-home use and produces reproducible, robust results on a battery of tests, including eyeblink conditioning, prepulse inhibition of acoustic startle response, and startle habituation. This approach provides a scalable, universal resource for quantitative assays of central nervous system function.</p>}},
  author       = {{Boele, H J and Jung, C and Sherry, S and Roggeveen, L E M and Dijkhuizen, S and Öhman, J and Abraham, E and Uvarov, A and Boele, C P and Gultig, K and Rasmussen, A and Vinueza-Veloz, M F and Medina, J F and Koekkoek, S K E and De Zeeuw, C I and Wang, S S-H}},
  issn         = {{2045-2322}},
  keywords     = {{Humans; Reflex, Startle/physiology; Smartphone; Acoustic Stimulation; Prepulse Inhibition; Habituation, Psychophysiologic}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Nature Publishing Group}},
  series       = {{Scientific Reports}},
  title        = {{Accessible and reliable neurometric testing in humans using a smartphone platform}},
  url          = {{http://dx.doi.org/10.1038/s41598-023-49568-2}},
  doi          = {{10.1038/s41598-023-49568-2}},
  volume       = {{13}},
  year         = {{2023}},
}