Population-based data from the Swedish Colon Cancer Registry
(2013) In British Journal of Surgery 100(8). p.1100-1107- Abstract
- Background Evaluating the external validity of clinical trials requires knowledge not only of the study population but also of a relevant reference population. The main aim of this study was to present data from a large, contemporary, population-based cohort of patients with colonic cancer. Methods Data on patients diagnosed between 2007 and 2011 were extracted from the Swedish Colon Cancer Registry. The data, registered prospectively in a national population of almost 10 million, included over 99 per cent of all diagnosed adenocarcinomas of the colon. Results This analysis included 18889 patients with 19526 tumours (3 center dot 0 per cent had synchronous tumours). The sex distribution was fairly equal, and the median age was 74 center... (More)
- Background Evaluating the external validity of clinical trials requires knowledge not only of the study population but also of a relevant reference population. The main aim of this study was to present data from a large, contemporary, population-based cohort of patients with colonic cancer. Methods Data on patients diagnosed between 2007 and 2011 were extracted from the Swedish Colon Cancer Registry. The data, registered prospectively in a national population of almost 10 million, included over 99 per cent of all diagnosed adenocarcinomas of the colon. Results This analysis included 18889 patients with 19526 tumours (3 center dot 0 per cent had synchronous tumours). The sex distribution was fairly equal, and the median age was 74 center dot 1 (interquartile range 65-81) years. The overall and relative (cancer-specific) survival rates after 3 years were 62 center dot 7 and 71 center dot 4 per cent respectively. Some 88 center dot 0 per cent of the patients were operated on, and 83 center dot 8 per cent had tumours resected. Median blood loss during bowel resection was 200 (mean 311) ml, and the median operating time was 160min; 5 center dot 6 per cent of the procedures were laparoscopic. Preoperative chemotherapy was administered to 2 center dot 1 per cent of patients; postoperative chemotherapy was planned in 90 center dot 1 per cent of fit patients aged less than 75 years with stage III disease. In patients operated on in an emergency setting (21 center dot 5 per cent), the preoperative evaluation was less extensive, the proportion of R0 resections was lower, and the outcomes were poorer, in both the short and long term. Conclusion These population-based data represent good-quality reference points. (Less)
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- author
- Kodeda, K. ; Nathanaelsson, L. ; Jung, B. ; Olsson, H. ; Jestin, P. ; Sjovall, A. ; Glimelius, B. ; Pahlman, L. and Syk, Ingvar LU
- organization
- publishing date
- 2013
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- Contribution to journal
- publication status
- published
- subject
- in
- British Journal of Surgery
- volume
- 100
- issue
- 8
- pages
- 1100 - 1107
- publisher
- Oxford University Press
- external identifiers
-
- wos:000320132300019
- scopus:84878822248
- pmid:23696510
- ISSN
- 1365-2168
- DOI
- 10.1002/bjs.9166
- language
- English
- LU publication?
- yes
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- bc953bba-2cb1-4bba-8222-57ac81f77e49 (old id 3980039)
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- 2016-04-01 10:27:54
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- 2022-04-27 22:14:09
@article{bc953bba-2cb1-4bba-8222-57ac81f77e49,
abstract = {{Background Evaluating the external validity of clinical trials requires knowledge not only of the study population but also of a relevant reference population. The main aim of this study was to present data from a large, contemporary, population-based cohort of patients with colonic cancer. Methods Data on patients diagnosed between 2007 and 2011 were extracted from the Swedish Colon Cancer Registry. The data, registered prospectively in a national population of almost 10 million, included over 99 per cent of all diagnosed adenocarcinomas of the colon. Results This analysis included 18889 patients with 19526 tumours (3 center dot 0 per cent had synchronous tumours). The sex distribution was fairly equal, and the median age was 74 center dot 1 (interquartile range 65-81) years. The overall and relative (cancer-specific) survival rates after 3 years were 62 center dot 7 and 71 center dot 4 per cent respectively. Some 88 center dot 0 per cent of the patients were operated on, and 83 center dot 8 per cent had tumours resected. Median blood loss during bowel resection was 200 (mean 311) ml, and the median operating time was 160min; 5 center dot 6 per cent of the procedures were laparoscopic. Preoperative chemotherapy was administered to 2 center dot 1 per cent of patients; postoperative chemotherapy was planned in 90 center dot 1 per cent of fit patients aged less than 75 years with stage III disease. In patients operated on in an emergency setting (21 center dot 5 per cent), the preoperative evaluation was less extensive, the proportion of R0 resections was lower, and the outcomes were poorer, in both the short and long term. Conclusion These population-based data represent good-quality reference points.}},
author = {{Kodeda, K. and Nathanaelsson, L. and Jung, B. and Olsson, H. and Jestin, P. and Sjovall, A. and Glimelius, B. and Pahlman, L. and Syk, Ingvar}},
issn = {{1365-2168}},
language = {{eng}},
number = {{8}},
pages = {{1100--1107}},
publisher = {{Oxford University Press}},
series = {{British Journal of Surgery}},
title = {{Population-based data from the Swedish Colon Cancer Registry}},
url = {{http://dx.doi.org/10.1002/bjs.9166}},
doi = {{10.1002/bjs.9166}},
volume = {{100}},
year = {{2013}},
}