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Viable/non-viable cell assay using electrokinetic deterministic lateral displacement

Ho, Bao D. LU ; Beech, Jason P. LU and Tegenfeldt, Jonas O. LU orcid (2019) 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 In 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 p.596-597
Abstract

To evaluate the effect of antibiotic drugs, it is important that the cells that are killed can be sorted from the cells that are resistant to the antibiotics. Here we report a simple label-free method for the continuous separation of viable/non-viable cells using Electrokinetic Deterministic Lateral Displacement. In general, this opens up for continuous sorting of a population of cells that is homogeneous in size but heterogeneous in surface charge or dielectric properties, properties that change as a function of viability.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Deterministic Lateral Displacement, DLD, Electrokinetics, Label-free cell separation
host publication
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
series title
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
pages
2 pages
publisher
Chemical and Biological Microsystems Society
conference name
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
conference location
Basel, Switzerland
conference dates
2019-10-27 - 2019-10-31
external identifiers
  • scopus:85094953457
ISBN
9781733419000
language
English
LU publication?
yes
id
bcea8a5a-74b2-452a-b1ed-3225a12304e1
date added to LUP
2020-11-24 08:06:19
date last changed
2023-10-22 20:50:02
@inproceedings{bcea8a5a-74b2-452a-b1ed-3225a12304e1,
  abstract     = {{<p>To evaluate the effect of antibiotic drugs, it is important that the cells that are killed can be sorted from the cells that are resistant to the antibiotics. Here we report a simple label-free method for the continuous separation of viable/non-viable cells using Electrokinetic Deterministic Lateral Displacement. In general, this opens up for continuous sorting of a population of cells that is homogeneous in size but heterogeneous in surface charge or dielectric properties, properties that change as a function of viability.</p>}},
  author       = {{Ho, Bao D. and Beech, Jason P. and Tegenfeldt, Jonas O.}},
  booktitle    = {{23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019}},
  isbn         = {{9781733419000}},
  keywords     = {{Deterministic Lateral Displacement; DLD; Electrokinetics; Label-free cell separation}},
  language     = {{eng}},
  pages        = {{596--597}},
  publisher    = {{Chemical and Biological Microsystems Society}},
  series       = {{23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019}},
  title        = {{Viable/non-viable cell assay using electrokinetic deterministic lateral displacement}},
  year         = {{2019}},
}