Advanced

Alterations in Multiple Lifestyle Factors in Subjects with the Metabolic Syndrome Independently of Obesity

Roos, Vendela; Elmståhl, Sölve LU ; Ingelsson, Erik; Sundström, Johan; Ärnlöv, Johan and Lind, Lars (2017) In Metabolic syndrome and related disorders 15(3). p.118-123
Abstract

BACKGROUND: Many lifestyle factors have been associated with the metabolic syndrome (MetS). However, most of these studies have not considered the potential impact of obesity and have often only investigated one lifestyle factor at the time. We aimed to investigate the interplay between body mass index (BMI) and MetS with respect to multiple lifestyle factors.

METHODS: BMI and MetS [National Cholesterol Education Program (NCEP)/Adult Treatment Panel III criteria] were assessed in a sample of 18,880 subjects aged 45-75 years from the population-based EpiHealth study. Participants were categorized into six groups according to BMI category (normal weight/BMI <25 kg/m2, overweight/BMI 25-30 kg/m2, and obesity/BMI >30 kg/m2) and... (More)

BACKGROUND: Many lifestyle factors have been associated with the metabolic syndrome (MetS). However, most of these studies have not considered the potential impact of obesity and have often only investigated one lifestyle factor at the time. We aimed to investigate the interplay between body mass index (BMI) and MetS with respect to multiple lifestyle factors.

METHODS: BMI and MetS [National Cholesterol Education Program (NCEP)/Adult Treatment Panel III criteria] were assessed in a sample of 18,880 subjects aged 45-75 years from the population-based EpiHealth study. Participants were categorized into six groups according to BMI category (normal weight/BMI <25 kg/m2, overweight/BMI 25-30 kg/m2, and obesity/BMI >30 kg/m2) and MetS status (+/-, NCEP criteria). A wide range of lifestyle factors related to physical activity, smoking, alcohol, sleep quality, working conditions, quality of life and stress, and eating patterns were assessed using a questionnaire.

RESULTS: Prevalent MetS (23% in the sample) was associated with less physical activity (P < 0.0001), more TV watching (P < 0.0001), more years of smoking (P < 0.0001), lower education level (P = 0.007), and experiencing a poor general quality of life (P < 0.0001). These lifestyle factors were all associated with MetS, independently of each other and independently of BMI. Similar results were generated when number of MetS components and presence/absence of individual MetS components were used as outcomes.

CONCLUSIONS: This cross-sectional study identified alterations in a number of lifestyle factors associated with MetS independently of each other and independently of BMI. Future longitudinal studies are needed to assess causal and temporal relationships between lifestyle factors and MetS development.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
lifestyle factors, metabolic syndrome, MHO, obesity
in
Metabolic syndrome and related disorders
volume
15
issue
3
pages
6 pages
publisher
Mary Ann Liebert, Inc.
external identifiers
  • scopus:85040507598
ISSN
1557-8518
DOI
10.1089/met.2016.0120
language
English
LU publication?
yes
id
bd27dc80-ae06-43ba-85f9-b7acb47849eb
date added to LUP
2018-02-05 16:03:49
date last changed
2018-05-29 10:21:09
@article{bd27dc80-ae06-43ba-85f9-b7acb47849eb,
  abstract     = {<p>BACKGROUND: Many lifestyle factors have been associated with the metabolic syndrome (MetS). However, most of these studies have not considered the potential impact of obesity and have often only investigated one lifestyle factor at the time. We aimed to investigate the interplay between body mass index (BMI) and MetS with respect to multiple lifestyle factors.</p><p>METHODS: BMI and MetS [National Cholesterol Education Program (NCEP)/Adult Treatment Panel III criteria] were assessed in a sample of 18,880 subjects aged 45-75 years from the population-based EpiHealth study. Participants were categorized into six groups according to BMI category (normal weight/BMI &lt;25 kg/m2, overweight/BMI 25-30 kg/m2, and obesity/BMI &gt;30 kg/m2) and MetS status (+/-, NCEP criteria). A wide range of lifestyle factors related to physical activity, smoking, alcohol, sleep quality, working conditions, quality of life and stress, and eating patterns were assessed using a questionnaire.</p><p>RESULTS: Prevalent MetS (23% in the sample) was associated with less physical activity (P &lt; 0.0001), more TV watching (P &lt; 0.0001), more years of smoking (P &lt; 0.0001), lower education level (P = 0.007), and experiencing a poor general quality of life (P &lt; 0.0001). These lifestyle factors were all associated with MetS, independently of each other and independently of BMI. Similar results were generated when number of MetS components and presence/absence of individual MetS components were used as outcomes.</p><p>CONCLUSIONS: This cross-sectional study identified alterations in a number of lifestyle factors associated with MetS independently of each other and independently of BMI. Future longitudinal studies are needed to assess causal and temporal relationships between lifestyle factors and MetS development.</p>},
  author       = {Roos, Vendela and Elmståhl, Sölve and Ingelsson, Erik and Sundström, Johan and Ärnlöv, Johan and Lind, Lars},
  issn         = {1557-8518},
  keyword      = {lifestyle factors,metabolic syndrome,MHO,obesity},
  language     = {eng},
  month        = {04},
  number       = {3},
  pages        = {118--123},
  publisher    = {Mary Ann Liebert, Inc.},
  series       = {Metabolic syndrome and related disorders},
  title        = {Alterations in Multiple Lifestyle Factors in Subjects with the Metabolic Syndrome Independently of Obesity},
  url          = {http://dx.doi.org/10.1089/met.2016.0120},
  volume       = {15},
  year         = {2017},
}