Improved Age- and Gender-Specific Radiation Risk Models Applied on Cohorts of Swedish Patients
(2021) In Radiation Protection Dosimetry 195(44624). p.334-338- Abstract
The aim of this study is to implement lifetime attributable risk (LAR) predictions for radiation induced cancers for Swedish cohorts of patients of various age and sex, undergoing diagnostic investigations by nuclear medicine methods.
METHODS: Calculations are performed on Swedish groups of patients with Paget's disease and with bone metastases from prostatic cancer and diagnosed with bone scintigraphy with an administration of 500 MBq 99mTc-phosphonate.
RESULTS: The inclusion of patient survival rates into the calculations lowers the induced radiation cancer risk, as it takes into account that cohorts of patients have shorter predicted survival times than the general population.
CONCLUSION: LAR estimations could be... (More)
The aim of this study is to implement lifetime attributable risk (LAR) predictions for radiation induced cancers for Swedish cohorts of patients of various age and sex, undergoing diagnostic investigations by nuclear medicine methods.
METHODS: Calculations are performed on Swedish groups of patients with Paget's disease and with bone metastases from prostatic cancer and diagnosed with bone scintigraphy with an administration of 500 MBq 99mTc-phosphonate.
RESULTS: The inclusion of patient survival rates into the calculations lowers the induced radiation cancer risk, as it takes into account that cohorts of patients have shorter predicted survival times than the general population.
CONCLUSION: LAR estimations could be valuable for referring physicians, nuclear medicine physicians, nurses, medical physicists, radiologists, and oncologists and as well as ethical committees for risk estimates for specific subgroups of patients. Caution is however advised with respect to application of LAR predictions to individuals (because of individual sensitivities, circumstances, etc.).
(Less)
- author
- Andersson, Martin LU ; Eckerman, Keith ; Pawel, David ; Almén, Anja LU and Mattsson, Sören LU
- organization
- publishing date
- 2021-05-29
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Radiation Protection Dosimetry
- volume
- 195
- issue
- 44624
- pages
- 334 - 338
- publisher
- Oxford University Press
- external identifiers
-
- pmid:34056661
- scopus:85118597976
- ISSN
- 1742-3406
- DOI
- 10.1093/rpd/ncab075
- language
- English
- LU publication?
- yes
- id
- bd792b6a-efb5-4d69-a6fa-b0a489607740
- date added to LUP
- 2021-07-09 00:18:57
- date last changed
- 2024-06-29 14:25:32
@article{bd792b6a-efb5-4d69-a6fa-b0a489607740,
abstract = {{<p>The aim of this study is to implement lifetime attributable risk (LAR) predictions for radiation induced cancers for Swedish cohorts of patients of various age and sex, undergoing diagnostic investigations by nuclear medicine methods.</p><p>METHODS: Calculations are performed on Swedish groups of patients with Paget's disease and with bone metastases from prostatic cancer and diagnosed with bone scintigraphy with an administration of 500 MBq 99mTc-phosphonate.</p><p>RESULTS: The inclusion of patient survival rates into the calculations lowers the induced radiation cancer risk, as it takes into account that cohorts of patients have shorter predicted survival times than the general population.</p><p>CONCLUSION: LAR estimations could be valuable for referring physicians, nuclear medicine physicians, nurses, medical physicists, radiologists, and oncologists and as well as ethical committees for risk estimates for specific subgroups of patients. Caution is however advised with respect to application of LAR predictions to individuals (because of individual sensitivities, circumstances, etc.).</p>}},
author = {{Andersson, Martin and Eckerman, Keith and Pawel, David and Almén, Anja and Mattsson, Sören}},
issn = {{1742-3406}},
language = {{eng}},
month = {{05}},
number = {{44624}},
pages = {{334--338}},
publisher = {{Oxford University Press}},
series = {{Radiation Protection Dosimetry}},
title = {{Improved Age- and Gender-Specific Radiation Risk Models Applied on Cohorts of Swedish Patients}},
url = {{http://dx.doi.org/10.1093/rpd/ncab075}},
doi = {{10.1093/rpd/ncab075}},
volume = {{195}},
year = {{2021}},
}