Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Glutamate dehydrogenase, insulin secretion and Type 2 Diabetes. A new means to protect the pancreatic β-cell?

Göhring, Isabel LU and Mulder, Hindrik LU orcid (2012) In Journal of Endocrinology 212(3). p.239-242
Abstract
In this issue of Journal of Endocrinology, Dr Han and colleagues report a protective effect of the glutamate dehydrogenase-activator BCH under diabetes-like conditions that impair β-cell function in both a pancreatic β-cell line and in db/db mice. Based on these observations, the authors suggest that BCH could serve as novel treatment modality in Type 2 Diabetes. The present commentary discusses the importance of the findings. Some additional questions are raised, that may be addressed in future investigations, as is some concern regarding BCH treatment of β-cell failure.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Journal of Endocrinology
volume
212
issue
3
pages
239 - 242
publisher
Society for Endocrinology
external identifiers
  • wos:000302116400001
  • pmid:22232141
  • scopus:84857839613
  • pmid:22232141
ISSN
1479-6805
DOI
10.1530/JOE-11-0481
language
English
LU publication?
yes
id
bd81debf-5c1b-4810-bb03-9ea0e0577051 (old id 2336591)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/22232141?dopt=Abstract
date added to LUP
2016-04-01 10:52:34
date last changed
2022-02-02 21:51:10
@article{bd81debf-5c1b-4810-bb03-9ea0e0577051,
  abstract     = {{In this issue of Journal of Endocrinology, Dr Han and colleagues report a protective effect of the glutamate dehydrogenase-activator BCH under diabetes-like conditions that impair β-cell function in both a pancreatic β-cell line and in db/db mice. Based on these observations, the authors suggest that BCH could serve as novel treatment modality in Type 2 Diabetes. The present commentary discusses the importance of the findings. Some additional questions are raised, that may be addressed in future investigations, as is some concern regarding BCH treatment of β-cell failure.}},
  author       = {{Göhring, Isabel and Mulder, Hindrik}},
  issn         = {{1479-6805}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{239--242}},
  publisher    = {{Society for Endocrinology}},
  series       = {{Journal of Endocrinology}},
  title        = {{Glutamate dehydrogenase, insulin secretion and Type 2 Diabetes. A new means to protect the pancreatic β-cell?}},
  url          = {{http://dx.doi.org/10.1530/JOE-11-0481}},
  doi          = {{10.1530/JOE-11-0481}},
  volume       = {{212}},
  year         = {{2012}},
}