Advanced

The nation-wide Swedish family-cancer database--updated structure and familial rates

Hemminki, K LU ; Li, Xinjun LU ; Plna, K; Granström, C and Vaittinen, P (2001) In Acta oncologica (Stockholm, Sweden) 40(6). p.7-772
Abstract

The Swedish Family-Cancer Database was expanded to include all Swedes born in 1932 and later (offspring) with their parents, totaling 10.2 million individuals. Cancer cases were retrieved from the Swedish Cancer Registry from the years 1958 to 1998, including over 1 million primary cancers and in situ tumors. Some 10%, of offspring diagnosed with cancer lack any parental information. Incidence rates of cancers were similar in the database and in the Cancer Registry to age 70, but at higher ages the rates in the Database were lower, probably because of selection. The familial risk for all types of cancer in offspring was 1.73 when a parent had the same type of cancer. The familial rates were increased for all main cancer sites, except... (More)

The Swedish Family-Cancer Database was expanded to include all Swedes born in 1932 and later (offspring) with their parents, totaling 10.2 million individuals. Cancer cases were retrieved from the Swedish Cancer Registry from the years 1958 to 1998, including over 1 million primary cancers and in situ tumors. Some 10%, of offspring diagnosed with cancer lack any parental information. Incidence rates of cancers were similar in the database and in the Cancer Registry to age 70, but at higher ages the rates in the Database were lower, probably because of selection. The familial risk for all types of cancer in offspring was 1.73 when a parent had the same type of cancer. The familial rates were increased for all main cancer sites, except for the upper aerodigestive tract, stomach, liver, pancreas and bone marrow (leukemia). The rates were 7.47 for thyroid, 4.69 for testis, and over 2.00 for melanoma, ovary, prostate, skin, endocrine glands and endometrium.

(Less)
Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescent, Adult, Aged, Aged, 80 and over, Child, Child, Preschool, Databases, Factual, Female, Humans, Incidence, Infant, Infant, Newborn, Male, Middle Aged, Neoplasms/epidemiology, Pedigree, Registries, Sweden/epidemiology
in
Acta oncologica (Stockholm, Sweden)
volume
40
issue
6
pages
6 pages
publisher
Taylor & Francis
external identifiers
  • scopus:0035191804
ISSN
0284-186X
DOI
10.1080/02841860152619214
language
English
LU publication?
no
id
bdbd312c-f1fe-4def-8524-c3df0942ae84
date added to LUP
2019-01-30 12:11:23
date last changed
2019-11-13 05:25:52
@article{bdbd312c-f1fe-4def-8524-c3df0942ae84,
  abstract     = {<p>The Swedish Family-Cancer Database was expanded to include all Swedes born in 1932 and later (offspring) with their parents, totaling 10.2 million individuals. Cancer cases were retrieved from the Swedish Cancer Registry from the years 1958 to 1998, including over 1 million primary cancers and in situ tumors. Some 10%, of offspring diagnosed with cancer lack any parental information. Incidence rates of cancers were similar in the database and in the Cancer Registry to age 70, but at higher ages the rates in the Database were lower, probably because of selection. The familial risk for all types of cancer in offspring was 1.73 when a parent had the same type of cancer. The familial rates were increased for all main cancer sites, except for the upper aerodigestive tract, stomach, liver, pancreas and bone marrow (leukemia). The rates were 7.47 for thyroid, 4.69 for testis, and over 2.00 for melanoma, ovary, prostate, skin, endocrine glands and endometrium.</p>},
  author       = {Hemminki, K and Li, Xinjun and Plna, K and Granström, C and Vaittinen, P},
  issn         = {0284-186X},
  keyword      = {Adolescent,Adult,Aged,Aged, 80 and over,Child,Child, Preschool,Databases, Factual,Female,Humans,Incidence,Infant,Infant, Newborn,Male,Middle Aged,Neoplasms/epidemiology,Pedigree,Registries,Sweden/epidemiology},
  language     = {eng},
  number       = {6},
  pages        = {7--772},
  publisher    = {Taylor & Francis},
  series       = {Acta oncologica (Stockholm, Sweden)},
  title        = {The nation-wide Swedish family-cancer database--updated structure and familial rates},
  url          = {http://dx.doi.org/10.1080/02841860152619214},
  volume       = {40},
  year         = {2001},
}