Metastasis-free survival after local recurrence of soft-tissue sarcoma
(1993) In Journal of Bone and Joint Surgery - Series B 75(4). p.658-660- Abstract
We analysed metastasis-free survival after local recurrence in a population-based series of 432 patients treated for soft-tissue sarcoma of the extremities or trunk wall. Local recurrence was found in 124 patients; of these, 73 had no detectable metastases when the last local recurrence was diagnosed. No patient received chemotherapy for local recurrence. The 73 patients had a 5-year metastasis-free survival rate of 0.73 after the last local recurrence, compared with 0.47 in all 124 patients with local recurrence. The 5-year metastasis-free survival rate was 0.76 in the 308 patients who had never developed local recurrence, and 0.68 in the whole series. The selection of patients with local recurrence but no concurrent metastasis creates... (More)
We analysed metastasis-free survival after local recurrence in a population-based series of 432 patients treated for soft-tissue sarcoma of the extremities or trunk wall. Local recurrence was found in 124 patients; of these, 73 had no detectable metastases when the last local recurrence was diagnosed. No patient received chemotherapy for local recurrence. The 73 patients had a 5-year metastasis-free survival rate of 0.73 after the last local recurrence, compared with 0.47 in all 124 patients with local recurrence. The 5-year metastasis-free survival rate was 0.76 in the 308 patients who had never developed local recurrence, and 0.68 in the whole series. The selection of patients with local recurrence but no concurrent metastasis creates a subset of the population with a good prognosis; this makes it difficult to evaluate the effect of treatment for local recurrence on survival rate. In studies of prognosis this group of patients should be analysed separately from patients with primary tumours.
(Less)
- author
- Gustafson, P. LU ; Dreinhofer, K. E. and Rydholm, A. LU
- publishing date
- 1993-01-01
- type
- Contribution to journal
- publication status
- published
- in
- Journal of Bone and Joint Surgery - Series B
- volume
- 75
- issue
- 4
- pages
- 3 pages
- publisher
- British Editorial Society of Bone & Joint Surgery
- external identifiers
-
- scopus:0027282598
- pmid:8331127
- ISSN
- 0301-620X
- language
- English
- LU publication?
- no
- id
- beadf672-1ef3-402e-b600-42f0270bc3d4
- date added to LUP
- 2019-05-25 07:56:22
- date last changed
- 2024-01-01 07:39:20
@article{beadf672-1ef3-402e-b600-42f0270bc3d4,
abstract = {{<p>We analysed metastasis-free survival after local recurrence in a population-based series of 432 patients treated for soft-tissue sarcoma of the extremities or trunk wall. Local recurrence was found in 124 patients; of these, 73 had no detectable metastases when the last local recurrence was diagnosed. No patient received chemotherapy for local recurrence. The 73 patients had a 5-year metastasis-free survival rate of 0.73 after the last local recurrence, compared with 0.47 in all 124 patients with local recurrence. The 5-year metastasis-free survival rate was 0.76 in the 308 patients who had never developed local recurrence, and 0.68 in the whole series. The selection of patients with local recurrence but no concurrent metastasis creates a subset of the population with a good prognosis; this makes it difficult to evaluate the effect of treatment for local recurrence on survival rate. In studies of prognosis this group of patients should be analysed separately from patients with primary tumours.</p>}},
author = {{Gustafson, P. and Dreinhofer, K. E. and Rydholm, A.}},
issn = {{0301-620X}},
language = {{eng}},
month = {{01}},
number = {{4}},
pages = {{658--660}},
publisher = {{British Editorial Society of Bone & Joint Surgery}},
series = {{Journal of Bone and Joint Surgery - Series B}},
title = {{Metastasis-free survival after local recurrence of soft-tissue sarcoma}},
volume = {{75}},
year = {{1993}},
}