Pre-vaccination seroprevalence of 15 human papillomavirus (HPV) types among women in the population-based Slovenian cervical screening program
(2013) In Vaccine 31(43). p.4935-4939- Abstract
- Objectives: To estimate seroprevalence of 11 high-risk (hr) HPV types and four low-risk (lr) HPV types among 20-64 years old Slovenian women participating in the population-based cervical cancer screening program. Methods: Serum samples from 3259 women were tested for HPV type-specific antibodies with a multiplexed pseudovirion-based serological assay (PsV-Luminex). Results: Seropositivity for any of the 15 HPV types was 65.7%, any of the 11 hr-HPV types 59.2%, and any of the four lr-HPV types 33.1%. Antibodies against at least one of the four vaccine HPV types (HPV 6, 11, 16, 18) were detected in 40.8% women. Among hr-HPV types, seropositivity was highest for HPV 16 (25.2%) and among lr-HPV types for HPV 6(19.1%). Age-specific HPV16... (More)
- Objectives: To estimate seroprevalence of 11 high-risk (hr) HPV types and four low-risk (lr) HPV types among 20-64 years old Slovenian women participating in the population-based cervical cancer screening program. Methods: Serum samples from 3259 women were tested for HPV type-specific antibodies with a multiplexed pseudovirion-based serological assay (PsV-Luminex). Results: Seropositivity for any of the 15 HPV types was 65.7%, any of the 11 hr-HPV types 59.2%, and any of the four lr-HPV types 33.1%. Antibodies against at least one of the four vaccine HPV types (HPV 6, 11, 16, 18) were detected in 40.8% women. Among hr-HPV types, seropositivity was highest for HPV 16 (25.2%) and among lr-HPV types for HPV 6(19.1%). Age-specific HPV16 seropositivity was highest among 30-39 years old (29.6%) and decreased with increasing age to 14.0% among 60-64 years old. Conclusion: The lifetime sexual exposure to genital HPV types is substantial, emphasising the need for HPV vaccination. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4212864
- author
- Ucakar, Veronika ; Jelen, Mateja M. ; Faust, Helena LU ; Poljak, Mario ; Dillner, Joakim LU and Klavs, Irena
- organization
- publishing date
- 2013
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- HPV, Seroprevalence, Cross-sectional study, Slovenia
- in
- Vaccine
- volume
- 31
- issue
- 43
- pages
- 4935 - 4939
- publisher
- Elsevier
- external identifiers
-
- wos:000326255400002
- scopus:84885125081
- pmid:23994822
- ISSN
- 1873-2518
- DOI
- 10.1016/j.vaccine.2013.08.038
- language
- English
- LU publication?
- yes
- id
- bf37f42b-3cc2-42b9-9215-580698c0dca7 (old id 4212864)
- date added to LUP
- 2016-04-01 10:32:46
- date last changed
- 2022-04-04 19:09:34
@article{bf37f42b-3cc2-42b9-9215-580698c0dca7, abstract = {{Objectives: To estimate seroprevalence of 11 high-risk (hr) HPV types and four low-risk (lr) HPV types among 20-64 years old Slovenian women participating in the population-based cervical cancer screening program. Methods: Serum samples from 3259 women were tested for HPV type-specific antibodies with a multiplexed pseudovirion-based serological assay (PsV-Luminex). Results: Seropositivity for any of the 15 HPV types was 65.7%, any of the 11 hr-HPV types 59.2%, and any of the four lr-HPV types 33.1%. Antibodies against at least one of the four vaccine HPV types (HPV 6, 11, 16, 18) were detected in 40.8% women. Among hr-HPV types, seropositivity was highest for HPV 16 (25.2%) and among lr-HPV types for HPV 6(19.1%). Age-specific HPV16 seropositivity was highest among 30-39 years old (29.6%) and decreased with increasing age to 14.0% among 60-64 years old. Conclusion: The lifetime sexual exposure to genital HPV types is substantial, emphasising the need for HPV vaccination. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.}}, author = {{Ucakar, Veronika and Jelen, Mateja M. and Faust, Helena and Poljak, Mario and Dillner, Joakim and Klavs, Irena}}, issn = {{1873-2518}}, keywords = {{HPV; Seroprevalence; Cross-sectional study; Slovenia}}, language = {{eng}}, number = {{43}}, pages = {{4935--4939}}, publisher = {{Elsevier}}, series = {{Vaccine}}, title = {{Pre-vaccination seroprevalence of 15 human papillomavirus (HPV) types among women in the population-based Slovenian cervical screening program}}, url = {{http://dx.doi.org/10.1016/j.vaccine.2013.08.038}}, doi = {{10.1016/j.vaccine.2013.08.038}}, volume = {{31}}, year = {{2013}}, }