A Web Portal for Communicating Polygenic Risk Score Results for Health Care Use—The P5 Study
(2021) In Frontiers in Genetics 12.- Abstract
We present a method for communicating personalized genetic risk information to citizens and their physicians using a secure web portal. We apply the method for 3,177 Finnish individuals in the P5 Study where estimates of genetic and absolute risk, based on genetic and clinical risk factors, of future disease are reported to study participants, allowing individuals to participate in managing their own health. Our method facilitates using polygenic risk score as a personalized tool to estimate a person’s future disease risk while offering a way for health care professionals to utilize the polygenic risk scores as a preventive tool in patient care.
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https://lup.lub.lu.se/record/c05944a1-12c2-42db-81fb-0b4b38fb7ab5
- author
- organization
- publishing date
- 2021-10-29
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- coronary heart disease, finhealth 2017 study, P5 study, polygenic risk sore, precision population health, type 2 diabetes, venous thromboembolism, web portal
- in
- Frontiers in Genetics
- volume
- 12
- article number
- 763159
- publisher
- Frontiers Media S. A.
- external identifiers
-
- scopus:85119034268
- pmid:34777479
- ISSN
- 1664-8021
- DOI
- 10.3389/fgene.2021.763159
- language
- English
- LU publication?
- yes
- additional info
- Publisher Copyright: Copyright © 2021 Marjonen, Marttila, Paajanen, Vornanen, Brunfeldt, Joensuu, Halmesvaara, Aro, Alanne-Kinnunen, Jousilahti, Borodulin, Koskinen, Tuomi, Ilanne-Parikka, Lindström, Laine, Auro, Kääriäinen, Perola and Kristiansson.
- id
- c05944a1-12c2-42db-81fb-0b4b38fb7ab5
- date added to LUP
- 2022-01-21 16:57:52
- date last changed
- 2024-09-22 09:14:40
@article{c05944a1-12c2-42db-81fb-0b4b38fb7ab5, abstract = {{<p>We present a method for communicating personalized genetic risk information to citizens and their physicians using a secure web portal. We apply the method for 3,177 Finnish individuals in the P5 Study where estimates of genetic and absolute risk, based on genetic and clinical risk factors, of future disease are reported to study participants, allowing individuals to participate in managing their own health. Our method facilitates using polygenic risk score as a personalized tool to estimate a person’s future disease risk while offering a way for health care professionals to utilize the polygenic risk scores as a preventive tool in patient care.</p>}}, author = {{Marjonen, Heidi and Marttila, Minttu and Paajanen, Teemu and Vornanen, Marleena and Brunfeldt, Minna and Joensuu, Anni and Halmesvaara, Otto and Aro, Kimmo and Alanne-Kinnunen, Mervi and Jousilahti, Pekka and Borodulin, Katja and Koskinen, Seppo and Tuomi, Tiinamaija and Ilanne-Parikka, Pirjo and Lindström, Jaana and Laine, Merja K. and Auro, Kirsi and Kääriäinen, Helena and Perola, Markus and Kristiansson, Kati}}, issn = {{1664-8021}}, keywords = {{coronary heart disease; finhealth 2017 study; P5 study; polygenic risk sore; precision population health; type 2 diabetes; venous thromboembolism; web portal}}, language = {{eng}}, month = {{10}}, publisher = {{Frontiers Media S. A.}}, series = {{Frontiers in Genetics}}, title = {{A Web Portal for Communicating Polygenic Risk Score Results for Health Care Use—The P5 Study}}, url = {{http://dx.doi.org/10.3389/fgene.2021.763159}}, doi = {{10.3389/fgene.2021.763159}}, volume = {{12}}, year = {{2021}}, }