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Factors associated with blood pressure control in Swedish primary care patients with hypertension : a cross-sectional study

Brodin, Niklas LU ; Wolff, Moa LU ; Borgström Bolmsjö, Beata LU ; Milos Nymberg, Veronica LU orcid ; Nymberg, Peter LU orcid and Calling, Susanna LU (2025) In Scandinavian Journal of Primary Health Care
Abstract

Purpose: This study aimed to investigate the factors associated with blood pressure control in a primary healthcare population with hypertension. Materials and methods: We used baseline data from a recent Swedish randomized controlled trial where 400 patients diagnosed with hypertension from 10 primary health care centers were included. The participants underwent blood pressure measurements, blood sampling and completed questionnaires on quality of life, physical activities, tobacco- and alcohol use, medication, and comorbidities. Logistic regression analyses were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for factors associated with blood pressure control (<140/90 mmHg). Results: The mean age of the... (More)

Purpose: This study aimed to investigate the factors associated with blood pressure control in a primary healthcare population with hypertension. Materials and methods: We used baseline data from a recent Swedish randomized controlled trial where 400 patients diagnosed with hypertension from 10 primary health care centers were included. The participants underwent blood pressure measurements, blood sampling and completed questionnaires on quality of life, physical activities, tobacco- and alcohol use, medication, and comorbidities. Logistic regression analyses were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for factors associated with blood pressure control (<140/90 mmHg). Results: The mean age of the participants was 69 years. The results showed blood pressure control in 41% of the cases. The factors that had the highest ORs for achieving blood pressure control were previous myocardial infarction (OR 2.44; CI 1.08–5.53), diabetes diagnosis (OR 2.26; CI 1.31–3.88), and use of ≥2 blood pressure medications (OR 1.62; CI 1.07–2.46). Family history of hypertension was negatively associated with blood pressure control (OR 0.29; CI 0.38–0.88) (univariate analyses). Conclusions: Our study found an association between the use of ≥2 antihypertensive medications and blood pressure control. Despite current treatment guidelines for hypertension, the use of single-drug therapy remains common. By shifting from single drug to combination therapy, focusing on patients with a family history of hypertension and those without comorbidities, the proportion achieving blood pressure control could increase significantly. Trial registration: ClinicalTrials.gov (NCT04407962).

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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
in press
subject
keywords
antihypertensive agents, blood pressure, combination drug therapy, Hypertension, primary health care
in
Scandinavian Journal of Primary Health Care
publisher
Informa Healthcare
external identifiers
  • scopus:105009508481
  • pmid:40583484
ISSN
0281-3432
DOI
10.1080/02813432.2025.2524366
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
id
c0b33534-6dbd-4f55-b6cd-52d1d053ab67
date added to LUP
2025-08-13 15:09:28
date last changed
2025-08-14 09:00:13
@article{c0b33534-6dbd-4f55-b6cd-52d1d053ab67,
  abstract     = {{<p>Purpose: This study aimed to investigate the factors associated with blood pressure control in a primary healthcare population with hypertension. Materials and methods: We used baseline data from a recent Swedish randomized controlled trial where 400 patients diagnosed with hypertension from 10 primary health care centers were included. The participants underwent blood pressure measurements, blood sampling and completed questionnaires on quality of life, physical activities, tobacco- and alcohol use, medication, and comorbidities. Logistic regression analyses were used to estimate odds ratios (OR) and 95% confidence intervals (CI) for factors associated with blood pressure control (&lt;140/90 mmHg). Results: The mean age of the participants was 69 years. The results showed blood pressure control in 41% of the cases. The factors that had the highest ORs for achieving blood pressure control were previous myocardial infarction (OR 2.44; CI 1.08–5.53), diabetes diagnosis (OR 2.26; CI 1.31–3.88), and use of ≥2 blood pressure medications (OR 1.62; CI 1.07–2.46). Family history of hypertension was negatively associated with blood pressure control (OR 0.29; CI 0.38–0.88) (univariate analyses). Conclusions: Our study found an association between the use of ≥2 antihypertensive medications and blood pressure control. Despite current treatment guidelines for hypertension, the use of single-drug therapy remains common. By shifting from single drug to combination therapy, focusing on patients with a family history of hypertension and those without comorbidities, the proportion achieving blood pressure control could increase significantly. Trial registration: ClinicalTrials.gov (NCT04407962).</p>}},
  author       = {{Brodin, Niklas and Wolff, Moa and Borgström Bolmsjö, Beata and Milos Nymberg, Veronica and Nymberg, Peter and Calling, Susanna}},
  issn         = {{0281-3432}},
  keywords     = {{antihypertensive agents; blood pressure; combination drug therapy; Hypertension; primary health care}},
  language     = {{eng}},
  publisher    = {{Informa Healthcare}},
  series       = {{Scandinavian Journal of Primary Health Care}},
  title        = {{Factors associated with blood pressure control in Swedish primary care patients with hypertension : a cross-sectional study}},
  url          = {{http://dx.doi.org/10.1080/02813432.2025.2524366}},
  doi          = {{10.1080/02813432.2025.2524366}},
  year         = {{2025}},
}