The mechanism of protein kinase C regulation
(2011) In Frontiers in Biology 6(4). p.328-336- Abstract
- Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4250285
- author
- Kazi, Julhash U. LU
- publishing date
- 2011
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- PKC biochemistry PKC kinase PKC phosphatases PKC structure
- in
- Frontiers in Biology
- volume
- 6
- issue
- 4
- pages
- 328 - 336
- publisher
- Higher Education Press
- external identifiers
-
- scopus:79961042749
- ISSN
- 1674-7984
- language
- English
- LU publication?
- no
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Experimental Clinical Chemistry (013016010)
- id
- c0b9f558-152b-4ff3-a8e0-a40ad7608671 (old id 4250285)
- alternative location
- http://link.springer.com/article/10.1007/s11515-011-1070-5
- date added to LUP
- 2016-04-04 14:41:42
- date last changed
- 2022-03-08 17:37:46
@article{c0b9f558-152b-4ff3-a8e0-a40ad7608671, abstract = {{Protein kinase C (PKC) is a family of serine/threonine protein kinases that plays a central role in transducing extracellular signals into a variety of intracellular responses ranging from cell proliferation to apoptosis. Nine PKC genes have been identified in the human genome, which encode 10 proteins. Each member of this protein kinase family displays distinct biochemical characteristics and is enriched in different cellular and subcellular locations. Activation of PKC has been implicated in the regulation of cell growth and differentiation. This review summarizes works of the past years in the field of PKC biochemistry that covers regulation and activation mechanism of different PKC isoforms.}}, author = {{Kazi, Julhash U.}}, issn = {{1674-7984}}, keywords = {{PKC biochemistry PKC kinase PKC phosphatases PKC structure}}, language = {{eng}}, number = {{4}}, pages = {{328--336}}, publisher = {{Higher Education Press}}, series = {{Frontiers in Biology}}, title = {{The mechanism of protein kinase C regulation}}, url = {{https://lup.lub.lu.se/search/files/6419144/4250507.pdf}}, volume = {{6}}, year = {{2011}}, }