Skin, soap, and spaghetti : Investigations of co-existing solid and liquid phases in organic materials using solid-state NMR with dynamics-based spectral editing
(2023) In Pure and Applied Chemistry 95(10). p.1075-1089- Abstract
Solid-state NMR methods incorporating dynamics-based spectral editing have a remarkable versatility for resolving and separately characterizing co-existing solid and liquid phases or domains in biologically and technically relevant organic materials. While 13C spectra acquired under magic-angle spinning and 1H decoupling provide atomic resolution, the signal intensities obtained with the CP and INEPT polarization transfer techniques give qualitative information about dynamics. This mini-review covers the basics of translational and rotational motion of atoms and molecules in organic materials, theoretical aspects of the relations between C-H bond reorientation and CP and INEPT signal intensities, and applications of the methods to a... (More)
Solid-state NMR methods incorporating dynamics-based spectral editing have a remarkable versatility for resolving and separately characterizing co-existing solid and liquid phases or domains in biologically and technically relevant organic materials. While 13C spectra acquired under magic-angle spinning and 1H decoupling provide atomic resolution, the signal intensities obtained with the CP and INEPT polarization transfer techniques give qualitative information about dynamics. This mini-review covers the basics of translational and rotational motion of atoms and molecules in organic materials, theoretical aspects of the relations between C-H bond reorientation and CP and INEPT signal intensities, and applications of the methods to a broad range of heterogeneous materials comprising hydrated assemblies of surfactants, lipids, proteins, and/or carbohydrates.
(Less)
- author
- Topgaard, Daniel LU
- organization
- publishing date
- 2023
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Hydration, lipids, molecular dynamics, NMR, proteins
- in
- Pure and Applied Chemistry
- volume
- 95
- issue
- 10
- pages
- 1075 - 1089
- publisher
- IUPAC
- external identifiers
-
- scopus:85164397308
- ISSN
- 0033-4545
- DOI
- 10.1515/pac-2023-0108
- language
- English
- LU publication?
- yes
- id
- c26495de-cde2-4c67-8ed4-90e28d19955b
- date added to LUP
- 2023-10-11 10:22:56
- date last changed
- 2024-01-09 15:45:47
@article{c26495de-cde2-4c67-8ed4-90e28d19955b,
abstract = {{<p>Solid-state NMR methods incorporating dynamics-based spectral editing have a remarkable versatility for resolving and separately characterizing co-existing solid and liquid phases or domains in biologically and technically relevant organic materials. While 13C spectra acquired under magic-angle spinning and 1H decoupling provide atomic resolution, the signal intensities obtained with the CP and INEPT polarization transfer techniques give qualitative information about dynamics. This mini-review covers the basics of translational and rotational motion of atoms and molecules in organic materials, theoretical aspects of the relations between C-H bond reorientation and CP and INEPT signal intensities, and applications of the methods to a broad range of heterogeneous materials comprising hydrated assemblies of surfactants, lipids, proteins, and/or carbohydrates.</p>}},
author = {{Topgaard, Daniel}},
issn = {{0033-4545}},
keywords = {{Hydration; lipids; molecular dynamics; NMR; proteins}},
language = {{eng}},
number = {{10}},
pages = {{1075--1089}},
publisher = {{IUPAC}},
series = {{Pure and Applied Chemistry}},
title = {{Skin, soap, and spaghetti : Investigations of co-existing solid and liquid phases in organic materials using solid-state NMR with dynamics-based spectral editing}},
url = {{http://dx.doi.org/10.1515/pac-2023-0108}},
doi = {{10.1515/pac-2023-0108}},
volume = {{95}},
year = {{2023}},
}