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Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients

Rasmuson, Erika ; Bengtsson, Boel LU ; Lindén, Christina ; Heijl, Anders LU ; Aspberg, Johan LU orcid ; ANDERSSON GEIMER, SABINA LU and Johannesson, Gauti LU (2023) In Acta Ophthalmologica p.17-17
Abstract
Purpose
To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).

Methods
Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP
Results
Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to... (More)
Purpose
To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).

Methods
Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP
Results
Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to follow-up during the 60 months. After exclusion of eyes that received increased therapy during follow-up, the IOP was significantly reduced at all visits up to 48 months in eyes with pre-LTP IOP ≥15 mmHg; 2.6 ± 3.1 mmHg at 1 month and 1.7 ± 2.8 mmHg at 48 months, n = 56 and 48, respectively. No significant IOP reduction was seen in eyes with pre-LTP IOP
Conclusion
LTP performed in multi-treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was ≥15 mmHg, but if the pre-laser IOP was lower than that, chances of LTP success were small. (Less)
Please use this url to cite or link to this publication:
author
; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
in
Acta Ophthalmologica
pages
17 - 17
publisher
Wiley-Blackwell
external identifiers
  • scopus:85161487517
  • pmid:37278271
ISSN
1755-3768
DOI
10.1111/aos.15718
language
English
LU publication?
yes
id
c43135df-13a2-49bc-8297-236b30eb1855
date added to LUP
2023-08-14 15:30:34
date last changed
2023-11-14 03:00:13
@article{c43135df-13a2-49bc-8297-236b30eb1855,
  abstract     = {{Purpose<br/>To evaluate the long-term effect of laser trabeculoplasty (LTP) in patients randomized to multi-treatment in the Glaucoma Intensive Treatment Study (GITS).<br/><br/>Methods<br/>Patients with untreated newly diagnosed open-angle glaucoma were treated with three intraocular pressure (IOP)-lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60-month study period. Our previous report on 12 months follow-up data revealed no effect of LTP in eyes having an IOP <br/>Results<br/>Before LTP, the mean IOP ± standard deviation in all 152 study-eyes of 122 multi-treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to follow-up during the 60 months. After exclusion of eyes that received increased therapy during follow-up, the IOP was significantly reduced at all visits up to 48 months in eyes with pre-LTP IOP ≥15 mmHg; 2.6 ± 3.1 mmHg at 1 month and 1.7 ± 2.8 mmHg at 48 months, n = 56 and 48, respectively. No significant IOP reduction was seen in eyes with pre-LTP IOP <br/>Conclusion<br/>LTP performed in multi-treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was ≥15 mmHg, but if the pre-laser IOP was lower than that, chances of LTP success were small.}},
  author       = {{Rasmuson, Erika and Bengtsson, Boel and Lindén, Christina and Heijl, Anders and Aspberg, Johan and ANDERSSON GEIMER, SABINA and Johannesson, Gauti}},
  issn         = {{1755-3768}},
  language     = {{eng}},
  pages        = {{17--17}},
  publisher    = {{Wiley-Blackwell}},
  series       = {{Acta Ophthalmologica}},
  title        = {{Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients}},
  url          = {{http://dx.doi.org/10.1111/aos.15718}},
  doi          = {{10.1111/aos.15718}},
  year         = {{2023}},
}