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Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy

Stafford, R Jason; Price, Roger E; Diederich, Chris J; Kangasniemi, Marko; Olsson, Lars E LU and Hazle, John D (2004) In Journal of Magnetic Resonance Imaging 20(4). p.14-706
Abstract

PURPOSE: To develop a multiplanar magnetic resonance temperature imaging (MRTI) technique based on interleaved gradient-echo echo-planar imaging (EPI), verify in phantom, develop software tools to process and display data on a clinical scanner in near real-time, and demonstrate feasibility to monitor ultrasound thermal ablation therapy in vivo.

MATERIALS AND METHODS: Temperature estimation used complex phase-difference subtraction of the EPI MRTI data to indirectly measure the temperature-dependent water proton-resonance-frequency shift. Software tools were developed to run on a clinical 1.5-T MR scanner that processed and displayed relevant temperature and thermal dosimetry data during the course of thermal ablation treatments in... (More)

PURPOSE: To develop a multiplanar magnetic resonance temperature imaging (MRTI) technique based on interleaved gradient-echo echo-planar imaging (EPI), verify in phantom, develop software tools to process and display data on a clinical scanner in near real-time, and demonstrate feasibility to monitor ultrasound thermal ablation therapy in vivo.

MATERIALS AND METHODS: Temperature estimation used complex phase-difference subtraction of the EPI MRTI data to indirectly measure the temperature-dependent water proton-resonance-frequency shift. Software tools were developed to run on a clinical 1.5-T MR scanner that processed and displayed relevant temperature and thermal dosimetry data during the course of thermal ablation treatments in canine brain and prostate in vivo.

RESULTS: EPI MRTI provided multi-planar acquisitions and increased temperature sensitivity and lipid suppression. Relative to a single-plane fast gradient-echo MRTI sequence at comparable spatial and temporal resolutions in phantom, EPI MRTI demonstrated a three-fold increase in sensitivity and slice coverage per TR. In vivo monitoring of ultrasound thermal ablation therapy in canine brain and prostate demonstrated the usefulness of the temperature and thermal dose information.

CONCLUSION: Multi-planar MRTI allowed progression of thermal damage to be monitored and treatment parameters adjusted in near real-time (less than five second delay). EPI MRTI is an effective multi-planar monitoring method during ultrasound thermal ablation procedures.

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Please use this url to cite or link to this publication:
author
publishing date
type
Contribution to journal
publication status
published
keywords
Animals, Brain, Dogs, Echo-Planar Imaging, Male, Monitoring, Physiologic, Phantoms, Imaging, Prostate, Sensitivity and Specificity, Software, Temperature, Ultrasonic Therapy
in
Journal of Magnetic Resonance Imaging
volume
20
issue
4
pages
9 pages
publisher
John Wiley & Sons
external identifiers
  • scopus:4744361555
ISSN
1053-1807
DOI
10.1002/jmri.20157
language
English
LU publication?
no
id
c44245fc-5293-49f6-9540-edcbdd35b51d
date added to LUP
2016-08-16 12:12:11
date last changed
2017-05-14 04:42:13
@article{c44245fc-5293-49f6-9540-edcbdd35b51d,
  abstract     = {<p>PURPOSE: To develop a multiplanar magnetic resonance temperature imaging (MRTI) technique based on interleaved gradient-echo echo-planar imaging (EPI), verify in phantom, develop software tools to process and display data on a clinical scanner in near real-time, and demonstrate feasibility to monitor ultrasound thermal ablation therapy in vivo.</p><p>MATERIALS AND METHODS: Temperature estimation used complex phase-difference subtraction of the EPI MRTI data to indirectly measure the temperature-dependent water proton-resonance-frequency shift. Software tools were developed to run on a clinical 1.5-T MR scanner that processed and displayed relevant temperature and thermal dosimetry data during the course of thermal ablation treatments in canine brain and prostate in vivo.</p><p>RESULTS: EPI MRTI provided multi-planar acquisitions and increased temperature sensitivity and lipid suppression. Relative to a single-plane fast gradient-echo MRTI sequence at comparable spatial and temporal resolutions in phantom, EPI MRTI demonstrated a three-fold increase in sensitivity and slice coverage per TR. In vivo monitoring of ultrasound thermal ablation therapy in canine brain and prostate demonstrated the usefulness of the temperature and thermal dose information.</p><p>CONCLUSION: Multi-planar MRTI allowed progression of thermal damage to be monitored and treatment parameters adjusted in near real-time (less than five second delay). EPI MRTI is an effective multi-planar monitoring method during ultrasound thermal ablation procedures.</p>},
  author       = {Stafford, R Jason and Price, Roger E and Diederich, Chris J and Kangasniemi, Marko and Olsson, Lars E and Hazle, John D},
  issn         = {1053-1807},
  keyword      = {Animals,Brain,Dogs,Echo-Planar Imaging,Male,Monitoring, Physiologic,Phantoms, Imaging,Prostate,Sensitivity and Specificity,Software,Temperature,Ultrasonic Therapy},
  language     = {eng},
  number       = {4},
  pages        = {14--706},
  publisher    = {John Wiley & Sons},
  series       = {Journal of Magnetic Resonance Imaging},
  title        = {Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy},
  url          = {http://dx.doi.org/10.1002/jmri.20157},
  volume       = {20},
  year         = {2004},
}