Clinical Application of the QRS-T Angle for the Prediction of Ventricular Arrhythmias in Patients with the Fontan Palliation
(2017) In Pediatric Cardiology 38(5). p.1049-1056- Abstract
Fontan palliation patients are at risk for ventricular arrhythmias post-operatively. This study aimed to evaluate whether differences in the spatial QRS-T angle can reliably predict ventricular arrhythmias in patients who had undergone Fontan palliation. A total of 117 patients who had the Fontan palliation and post-Fontan catheterization were included. Ventricular arrhythmias were identified in nine patients. Measurements of ECG parameters including QRS vector magnitude, QRS duration, corrected QT interval, and spatial peaks QRS-T angles were performed, and compared between those with and without ventricular arrhythmias. The only ECG parameter to distinguish those with versus those without VA was the SPQRS-T angle (p < 0.001), which... (More)
Fontan palliation patients are at risk for ventricular arrhythmias post-operatively. This study aimed to evaluate whether differences in the spatial QRS-T angle can reliably predict ventricular arrhythmias in patients who had undergone Fontan palliation. A total of 117 patients who had the Fontan palliation and post-Fontan catheterization were included. Ventricular arrhythmias were identified in nine patients. Measurements of ECG parameters including QRS vector magnitude, QRS duration, corrected QT interval, and spatial peaks QRS-T angles were performed, and compared between those with and without ventricular arrhythmias. The only ECG parameter to distinguish those with versus those without VA was the SPQRS-T angle (p < 0.001), which at a cut-off value of 102.9° gave sensitivity, specificity, positive and negative predictive values of 100.0, 57.0, 17.6 and 100.0%, respectively. Only the spatial peaks QRS-T angle differentiated those with and without ventricular arrhythmia development with a univariate HR 1.237 (95% CI 1.021–1.500) and a multivariate HR of 1.032 (1.009–1.056) when catheter measured parameters were taken into account. In Fontan patients, the spatial peaks QRS-T angle is a significant independent predictor of ventricular arrhythmias. Clinical usefulness of this parameter remains to be seen and should be tested prospectively.
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- author
- Tran, Tuong Vi and Cortez, Daniel LU
- organization
- publishing date
- 2017-04-29
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Fontan, Vectorcardiography, Ventricular arrhythmias
- in
- Pediatric Cardiology
- volume
- 38
- issue
- 5
- pages
- 8 pages
- publisher
- Springer
- external identifiers
-
- pmid:28456831
- wos:000402402600022
- scopus:85018319086
- ISSN
- 0172-0643
- DOI
- 10.1007/s00246-017-1618-5
- language
- English
- LU publication?
- yes
- id
- c49e7d7e-9075-4480-9550-6916d0dd1d3f
- date added to LUP
- 2017-05-24 16:12:40
- date last changed
- 2024-03-17 14:47:59
@article{c49e7d7e-9075-4480-9550-6916d0dd1d3f, abstract = {{<p>Fontan palliation patients are at risk for ventricular arrhythmias post-operatively. This study aimed to evaluate whether differences in the spatial QRS-T angle can reliably predict ventricular arrhythmias in patients who had undergone Fontan palliation. A total of 117 patients who had the Fontan palliation and post-Fontan catheterization were included. Ventricular arrhythmias were identified in nine patients. Measurements of ECG parameters including QRS vector magnitude, QRS duration, corrected QT interval, and spatial peaks QRS-T angles were performed, and compared between those with and without ventricular arrhythmias. The only ECG parameter to distinguish those with versus those without VA was the SPQRS-T angle (p < 0.001), which at a cut-off value of 102.9° gave sensitivity, specificity, positive and negative predictive values of 100.0, 57.0, 17.6 and 100.0%, respectively. Only the spatial peaks QRS-T angle differentiated those with and without ventricular arrhythmia development with a univariate HR 1.237 (95% CI 1.021–1.500) and a multivariate HR of 1.032 (1.009–1.056) when catheter measured parameters were taken into account. In Fontan patients, the spatial peaks QRS-T angle is a significant independent predictor of ventricular arrhythmias. Clinical usefulness of this parameter remains to be seen and should be tested prospectively.</p>}}, author = {{Tran, Tuong Vi and Cortez, Daniel}}, issn = {{0172-0643}}, keywords = {{Fontan; Vectorcardiography; Ventricular arrhythmias}}, language = {{eng}}, month = {{04}}, number = {{5}}, pages = {{1049--1056}}, publisher = {{Springer}}, series = {{Pediatric Cardiology}}, title = {{Clinical Application of the QRS-T Angle for the Prediction of Ventricular Arrhythmias in Patients with the Fontan Palliation}}, url = {{http://dx.doi.org/10.1007/s00246-017-1618-5}}, doi = {{10.1007/s00246-017-1618-5}}, volume = {{38}}, year = {{2017}}, }