Aortic vessel wall characteristics and blood pressure in children with intrauterine growth retardation and abnormal foetal aortic blood flow
(1997) In Acta Pædiatrica 86(3). p.299-305- Abstract
Blood pressure and pulsatile diameter changes of the abdominal aorta were measured in 68 children (mean age 9 years), with varying degrees of intrauterine growth retardation who were previously examined in their intrauterine life with Doppler velocimetry of the thoracic descending aorta. Diastolic blood pressure was lower (p < 0.05) and pulse pressure was increased (p < 0.01) in children with a birthweight small for gestational age as compared to those with a birthweight appropriate for gestational age. Systolic blood pressure was positively associated with relative increase in weight from birth up to the time of examination (p < 0.01), but not to early catch-up growth. Aortic vessel wall diameters were smaller in children born... (More)
Blood pressure and pulsatile diameter changes of the abdominal aorta were measured in 68 children (mean age 9 years), with varying degrees of intrauterine growth retardation who were previously examined in their intrauterine life with Doppler velocimetry of the thoracic descending aorta. Diastolic blood pressure was lower (p < 0.05) and pulse pressure was increased (p < 0.01) in children with a birthweight small for gestational age as compared to those with a birthweight appropriate for gestational age. Systolic blood pressure was positively associated with relative increase in weight from birth up to the time of examination (p < 0.01), but not to early catch-up growth. Aortic vessel wall diameters were smaller in children born small for gestational age, both before and after correction for current body surface area (p < 0.01). Blood pressure and aortic vessel wall characteristics exhibited no relationship to the foetal aortic Doppler wave-form. Changes in foetal haemodynamics associated with intrauterine growth retardation do not appear to contribute to a later increase in blood pressure. Within a group of foetuses with suspected growth retardation, increasing foetal weight deviation and a birthweight small for gestational age is associated with lower diastolic blood pressure at 9 years of age.
(Less)
- author
- Ley, D LU ; Stale, H LU and Marsal, K LU
- organization
- publishing date
- 1997-03
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Anthropometry, Aorta, Abdominal/embryology, Blood Flow Velocity, Blood Pressure, Body Weight, Child, Child, Preschool, Fetal Growth Retardation/diagnosis, Gestational Age, Hemodynamics, Humans, Infant, Infant, Newborn, Prospective Studies, Social Class
- in
- Acta Pædiatrica
- volume
- 86
- issue
- 3
- pages
- 299 - 305
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:0030959896
- pmid:9099321
- ISSN
- 0803-5253
- DOI
- 10.1111/j.1651-2227.1997.tb08894.x
- language
- English
- LU publication?
- yes
- id
- c534e2fb-2093-47ba-bc91-9aadd971d670
- date added to LUP
- 2021-02-15 18:53:39
- date last changed
- 2024-04-04 02:01:35
@article{c534e2fb-2093-47ba-bc91-9aadd971d670,
abstract = {{<p>Blood pressure and pulsatile diameter changes of the abdominal aorta were measured in 68 children (mean age 9 years), with varying degrees of intrauterine growth retardation who were previously examined in their intrauterine life with Doppler velocimetry of the thoracic descending aorta. Diastolic blood pressure was lower (p < 0.05) and pulse pressure was increased (p < 0.01) in children with a birthweight small for gestational age as compared to those with a birthweight appropriate for gestational age. Systolic blood pressure was positively associated with relative increase in weight from birth up to the time of examination (p < 0.01), but not to early catch-up growth. Aortic vessel wall diameters were smaller in children born small for gestational age, both before and after correction for current body surface area (p < 0.01). Blood pressure and aortic vessel wall characteristics exhibited no relationship to the foetal aortic Doppler wave-form. Changes in foetal haemodynamics associated with intrauterine growth retardation do not appear to contribute to a later increase in blood pressure. Within a group of foetuses with suspected growth retardation, increasing foetal weight deviation and a birthweight small for gestational age is associated with lower diastolic blood pressure at 9 years of age.</p>}},
author = {{Ley, D and Stale, H and Marsal, K}},
issn = {{0803-5253}},
keywords = {{Anthropometry; Aorta, Abdominal/embryology; Blood Flow Velocity; Blood Pressure; Body Weight; Child; Child, Preschool; Fetal Growth Retardation/diagnosis; Gestational Age; Hemodynamics; Humans; Infant; Infant, Newborn; Prospective Studies; Social Class}},
language = {{eng}},
number = {{3}},
pages = {{299--305}},
publisher = {{Wiley-Blackwell}},
series = {{Acta Pædiatrica}},
title = {{Aortic vessel wall characteristics and blood pressure in children with intrauterine growth retardation and abnormal foetal aortic blood flow}},
url = {{http://dx.doi.org/10.1111/j.1651-2227.1997.tb08894.x}},
doi = {{10.1111/j.1651-2227.1997.tb08894.x}},
volume = {{86}},
year = {{1997}},
}