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Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process

Kim, Tae Kyung ; Lee, Sang Wook LU ; Ahn, Ji-Young ; Laurell, Thomas LU ; Kim, So Youn and Jeong, Ok Chan (2011) In Japanese Journal of Applied Physics 50(6). p.05-06
Abstract
This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel "systematic evolution of ligands by exponential enrichment" (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during the SELEX process. The proposed device with an optimally designed hydraulic resistance-balanced channel network could be feasible and utilized as a multiplex selection module for a parallel SELEX process. (c) 2011 The Japan Society of Applied Physics
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author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Japanese Journal of Applied Physics
volume
50
issue
6
pages
05 - 06
publisher
Japan Society of Applied Physics
external identifiers
  • wos:000291748900105
  • scopus:79959457515
ISSN
0021-4922
DOI
10.1143/JJAP.50.06GL05
language
English
LU publication?
yes
id
c543fbec-040e-48db-b323-8a39d80b0017 (old id 2052597)
date added to LUP
2016-04-01 09:51:22
date last changed
2025-04-04 14:24:35
@article{c543fbec-040e-48db-b323-8a39d80b0017,
  abstract     = {{This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel "systematic evolution of ligands by exponential enrichment" (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during the SELEX process. The proposed device with an optimally designed hydraulic resistance-balanced channel network could be feasible and utilized as a multiplex selection module for a parallel SELEX process. (c) 2011 The Japan Society of Applied Physics}},
  author       = {{Kim, Tae Kyung and Lee, Sang Wook and Ahn, Ji-Young and Laurell, Thomas and Kim, So Youn and Jeong, Ok Chan}},
  issn         = {{0021-4922}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{05--06}},
  publisher    = {{Japan Society of Applied Physics}},
  series       = {{Japanese Journal of Applied Physics}},
  title        = {{Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process}},
  url          = {{http://dx.doi.org/10.1143/JJAP.50.06GL05}},
  doi          = {{10.1143/JJAP.50.06GL05}},
  volume       = {{50}},
  year         = {{2011}},
}