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Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia

Nielsen, T. Rune; Segers, Kurt; Vanderaspoilden, Valérie; Beinhoff, Ulrike; Minthon, Lennart LU ; Pissiota, Anna; Bekkhus-Wetterberg, Peter; Bjørkløf, Guro Hanevold; Tsolaki, Magda and Gkioka, Mara, et al. (2019) In International Journal of Geriatric Psychiatry
Abstract

Background: The aims of this study were to present the psychometric properties of a newly designed cognitive screening instrument, the Multicultural Cognitive Examination (MCE), and to compare it with the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural population. Methods: The study was a Western European cross-sectional multicenter study. The MCE consists of four components evaluating separate cognitive functions and was constructed by adding measures of memory, verbal fluency, and visuospatial function to the RUDAS to create a scale with 0 to 100 points. Results: A total of 66 patients with dementia and 123 cognitively intact participants were included across six memory clinics; 96 had minority ethnic... (More)

Background: The aims of this study were to present the psychometric properties of a newly designed cognitive screening instrument, the Multicultural Cognitive Examination (MCE), and to compare it with the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural population. Methods: The study was a Western European cross-sectional multicenter study. The MCE consists of four components evaluating separate cognitive functions and was constructed by adding measures of memory, verbal fluency, and visuospatial function to the RUDAS to create a scale with 0 to 100 points. Results: A total of 66 patients with dementia and 123 cognitively intact participants were included across six memory clinics; 96 had minority ethnic background, and 93 had majority ethnic background. Moderate to large differences were present between patients with dementia and control participants on all MCE components. The MCE significantly improved diagnostic accuracy compared with using the RUDAS alone, with area under the curves of.918,.984, and.991 for the RUDAS, MCE composite, and demographically corrected composite scores, respectively. Diagnostic accuracy of the MCE did not significantly differ between minority and majority ethnic groups. Across MCE subcomponents, patients with Alzheimer's disease (AD) dementia performed significantly poorer on the memory component compared with those with non-AD dementia. Conclusions: The MCE is a brief cross-cultural cognitive screening instrument that expands evaluation of the cognitive functions covered by the RUDAS, does not require any specialized training, and may be useful for classification of mild dementia or dementia subtypes.

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keywords
Alzheimer's disease, Cognitive assessment, dementia, diagnostic accuracy, ethnic groups, multicultural, RUDAS
in
International Journal of Geriatric Psychiatry
publisher
John Wiley and Sons Ltd
external identifiers
  • scopus:85064611788
ISSN
0885-6230
DOI
10.1002/gps.5099
language
English
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yes
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c73b7c87-655d-4793-a8e5-e85917bb00aa
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2019-05-07 12:27:12
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2019-05-28 03:57:59
@article{c73b7c87-655d-4793-a8e5-e85917bb00aa,
  abstract     = {<p>Background: The aims of this study were to present the psychometric properties of a newly designed cognitive screening instrument, the Multicultural Cognitive Examination (MCE), and to compare it with the Rowland Universal Dementia Assessment Scale (RUDAS) in a multicultural population. Methods: The study was a Western European cross-sectional multicenter study. The MCE consists of four components evaluating separate cognitive functions and was constructed by adding measures of memory, verbal fluency, and visuospatial function to the RUDAS to create a scale with 0 to 100 points. Results: A total of 66 patients with dementia and 123 cognitively intact participants were included across six memory clinics; 96 had minority ethnic background, and 93 had majority ethnic background. Moderate to large differences were present between patients with dementia and control participants on all MCE components. The MCE significantly improved diagnostic accuracy compared with using the RUDAS alone, with area under the curves of.918,.984, and.991 for the RUDAS, MCE composite, and demographically corrected composite scores, respectively. Diagnostic accuracy of the MCE did not significantly differ between minority and majority ethnic groups. Across MCE subcomponents, patients with Alzheimer's disease (AD) dementia performed significantly poorer on the memory component compared with those with non-AD dementia. Conclusions: The MCE is a brief cross-cultural cognitive screening instrument that expands evaluation of the cognitive functions covered by the RUDAS, does not require any specialized training, and may be useful for classification of mild dementia or dementia subtypes.</p>},
  author       = {Nielsen, T. Rune and Segers, Kurt and Vanderaspoilden, Valérie and Beinhoff, Ulrike and Minthon, Lennart and Pissiota, Anna and Bekkhus-Wetterberg, Peter and Bjørkløf, Guro Hanevold and Tsolaki, Magda and Gkioka, Mara and Waldemar, Gunhild},
  issn         = {0885-6230},
  keyword      = {Alzheimer's disease,Cognitive assessment,dementia,diagnostic accuracy,ethnic groups,multicultural,RUDAS},
  language     = {eng},
  month        = {03},
  publisher    = {John Wiley and Sons Ltd},
  series       = {International Journal of Geriatric Psychiatry},
  title        = {Validation of a brief Multicultural Cognitive Examination (MCE) for evaluation of dementia},
  url          = {http://dx.doi.org/10.1002/gps.5099},
  year         = {2019},
}