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Distribution and impact on quality of life of the pain modalities assessed by the King's Parkinson's disease pain scale

Martinez-Martin, Pablo ; Manuel Rojo-Abuin, Jose ; Rizos, Alexandra ; Rodriguez-Blazquez, Carmen ; Trenkwalder, Claudia ; Perkins, Lauren ; Sauerbier, Anna ; Odin, Per LU ; Antonini, Angelo and Chaudhuri, Kallol Ray (2017) In npj Parkinson's Disease 3. p.1-6
Abstract

In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients... (More)

In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients experienced more pain modalities than controls. In patients, Pain around joints (King's Parkinson's disease pain scale item 1) and Pain while turning in bed (item 8) were the most prevalent types of pain, whereas Burning mouth syndrome (item 11) and Pain due to grinding teeth (item 10) showed the lowest frequency. The total number of experienced pain modalities closely correlated with the PDQ-8 index, but not with other variables. For all pain types except Pain around joints (item 1) and pain related to Periodic leg movements/RLS (item 7), patients with pain had significantly worse health-related quality of life. The influence of pain, as a whole, on the health-related quality of life was not remarkable after adjustment by other variables. When the particular types of pain were considered, adjusted by sex, age, and Parkinson's disease duration, pain determinants were different for EQ-5D-3L and PDQ-8. King's Parkinson's disease pain scale allows exploring the distribution of the diverse syndromic pain occurring in Parkinson's disease and its association with health-related quality of life.

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publication status
published
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in
npj Parkinson's Disease
volume
3
article number
8
pages
1 - 6
external identifiers
  • pmid:28649608
ISSN
2373-8057
DOI
10.1038/s41531-017-0009-1
language
English
LU publication?
yes
id
c73c7939-2397-4fda-a4e2-2f7436c7d010
date added to LUP
2019-06-28 09:35:42
date last changed
2019-10-14 13:40:13
@article{c73c7939-2397-4fda-a4e2-2f7436c7d010,
  abstract     = {<p>In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom. The regular scores were used for the other analyses. Health-related quality of lifewas evaluated with EQ-5D-3L and PDQ-8 questionnaires. Parkinson's disease patients experienced more pain modalities than controls. In patients, Pain around joints (King's Parkinson's disease pain scale item 1) and Pain while turning in bed (item 8) were the most prevalent types of pain, whereas Burning mouth syndrome (item 11) and Pain due to grinding teeth (item 10) showed the lowest frequency. The total number of experienced pain modalities closely correlated with the PDQ-8 index, but not with other variables. For all pain types except Pain around joints (item 1) and pain related to Periodic leg movements/RLS (item 7), patients with pain had significantly worse health-related quality of life. The influence of pain, as a whole, on the health-related quality of life was not remarkable after adjustment by other variables. When the particular types of pain were considered, adjusted by sex, age, and Parkinson's disease duration, pain determinants were different for EQ-5D-3L and PDQ-8. King's Parkinson's disease pain scale allows exploring the distribution of the diverse syndromic pain occurring in Parkinson's disease and its association with health-related quality of life.</p>},
  author       = {Martinez-Martin, Pablo and Manuel Rojo-Abuin, Jose and Rizos, Alexandra and Rodriguez-Blazquez, Carmen and Trenkwalder, Claudia and Perkins, Lauren and Sauerbier, Anna and Odin, Per and Antonini, Angelo and Chaudhuri, Kallol Ray},
  issn         = {2373-8057},
  language     = {eng},
  pages        = {1--6},
  series       = {npj Parkinson's Disease},
  title        = {Distribution and impact on quality of life of the pain modalities assessed by the King's Parkinson's disease pain scale},
  url          = {http://dx.doi.org/10.1038/s41531-017-0009-1},
  doi          = {10.1038/s41531-017-0009-1},
  volume       = {3},
  year         = {2017},
}