Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Plasma Proteomic Profiling Reveals Alterations in Coagulation, Complement, and Extracellular Matrix Pathways in Orthostatic Hypotension

Johansson, Madeleine LU orcid ; Végvári, Ákos ; Engström, Gunnar LU and Fedorowski, Artur LU orcid (2026) In JACC: Advances 5(9).
Abstract
Which biological and molecular processes contribute to the pathophysiology of orthostatic hypotension? Orthostatic hypotension is associated with alterations in coagulation, complement, and extracellular matrix pathways, pointing to molecular effects beyond blood pressure regulation and broader vascular and inflammatory phenotypes.
Please use this url to cite or link to this publication:
author
; ; and
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Orthostatic hypotension, Blood pressure, Proteomics, Biomarkers, Coagulation, Blood clotting
in
JACC: Advances
volume
5
issue
9
article number
103116
publisher
American College of Cardiology
ISSN
2772-963X
DOI
10.1016/j.jacadv.2026.103116
project
Cardiovascular Dysautonomia and Syncope
Identifying novel pathomechanisms in classical orthostatic hypotension using unbiased, large-scale, plasma proteomic profiling
language
English
LU publication?
yes
id
c7ab5522-71d8-4ab9-ba60-726cbacb2e6f
date added to LUP
2026-08-12 00:33:40
date last changed
2026-08-13 02:51:53
@article{c7ab5522-71d8-4ab9-ba60-726cbacb2e6f,
  abstract     = {{Which biological and molecular processes contribute to the pathophysiology of orthostatic hypotension? Orthostatic hypotension is associated with alterations in coagulation, complement, and extracellular matrix pathways, pointing to molecular effects beyond blood pressure regulation and broader vascular and inflammatory phenotypes.}},
  author       = {{Johansson, Madeleine and Végvári, Ákos and Engström, Gunnar and Fedorowski, Artur}},
  issn         = {{2772-963X}},
  keywords     = {{Orthostatic hypotension; Blood pressure; Proteomics; Biomarkers; Coagulation; Blood clotting}},
  language     = {{eng}},
  month        = {{08}},
  number       = {{9}},
  publisher    = {{American College of Cardiology}},
  series       = {{JACC: Advances}},
  title        = {{Plasma Proteomic Profiling Reveals Alterations in Coagulation, Complement, and Extracellular Matrix Pathways in Orthostatic Hypotension}},
  url          = {{http://dx.doi.org/10.1016/j.jacadv.2026.103116}},
  doi          = {{10.1016/j.jacadv.2026.103116}},
  volume       = {{5}},
  year         = {{2026}},
}