Early postoperative fluid retention is a strong predictor for complications after pancreatoduodenectomy
(2019) In HPB 21(12). p.1784-1789- Abstract
Background: Perioperative fluid overload has been reported to increase complications after a variety of operative procedures. This study was conducted to investigate the incidence of fluid retention after pancreatic resection and its association with postoperative complications. Methods: Data from 1174 patients undergoing pancreatoduodenectomy between 2010 and 2016 were collected from the Swedish National Pancreatic and Periampullary Cancer Registry. Early postoperative fluid retention was defined as a weight gain ≥2 kg on postoperative day 1. Outcome measures were overall complications, as well as procedure-specific complications. Results: The weight change on postoperative day 1 ranged from −1 kg to +9 kg. A total of 782 patients... (More)
Background: Perioperative fluid overload has been reported to increase complications after a variety of operative procedures. This study was conducted to investigate the incidence of fluid retention after pancreatic resection and its association with postoperative complications. Methods: Data from 1174 patients undergoing pancreatoduodenectomy between 2010 and 2016 were collected from the Swedish National Pancreatic and Periampullary Cancer Registry. Early postoperative fluid retention was defined as a weight gain ≥2 kg on postoperative day 1. Outcome measures were overall complications, as well as procedure-specific complications. Results: The weight change on postoperative day 1 ranged from −1 kg to +9 kg. A total of 782 patients (66.6%) were considered to have early fluid retention. Patients with fluid retention had significantly higher rates of total complications (p = 0.002), surgical complications (p = 0.001), pancreatic anastomotic leakage (p = 0.018) and wound infection (p = 0.023). Multivariable logistic regression confirmed early fluid retention as an independent risk factor for total complications (OR 1.46; p = 0.003), surgical complications (OR 1.49; p = 0.002), pancreatic anastomotic leakage (OR 1.48; p = 0.027) and wound infection (OR 1.84; p = 0.023). Conclusions: Fluid retention is common after elective pancreatic resection, and its associated with an increased rate of postoperative complications.
(Less)
- author
- Åkerberg, Daniel LU ; Ansari, Daniel LU ; Bergenfeldt, Magnus LU ; Andersson, Roland LU and Tingstedt, Bobby LU
- organization
- publishing date
- 2019-12
- type
- Contribution to journal
- publication status
- published
- subject
- in
- HPB
- volume
- 21
- issue
- 12
- pages
- 5 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:31164275
- scopus:85066318554
- ISSN
- 1365-182X
- DOI
- 10.1016/j.hpb.2019.05.003
- language
- English
- LU publication?
- yes
- id
- cc0756c2-566b-4b76-8b7e-964e0502b9ef
- date added to LUP
- 2019-06-13 12:01:41
- date last changed
- 2024-04-30 12:26:51
@article{cc0756c2-566b-4b76-8b7e-964e0502b9ef,
abstract = {{<p>Background: Perioperative fluid overload has been reported to increase complications after a variety of operative procedures. This study was conducted to investigate the incidence of fluid retention after pancreatic resection and its association with postoperative complications. Methods: Data from 1174 patients undergoing pancreatoduodenectomy between 2010 and 2016 were collected from the Swedish National Pancreatic and Periampullary Cancer Registry. Early postoperative fluid retention was defined as a weight gain ≥2 kg on postoperative day 1. Outcome measures were overall complications, as well as procedure-specific complications. Results: The weight change on postoperative day 1 ranged from −1 kg to +9 kg. A total of 782 patients (66.6%) were considered to have early fluid retention. Patients with fluid retention had significantly higher rates of total complications (p = 0.002), surgical complications (p = 0.001), pancreatic anastomotic leakage (p = 0.018) and wound infection (p = 0.023). Multivariable logistic regression confirmed early fluid retention as an independent risk factor for total complications (OR 1.46; p = 0.003), surgical complications (OR 1.49; p = 0.002), pancreatic anastomotic leakage (OR 1.48; p = 0.027) and wound infection (OR 1.84; p = 0.023). Conclusions: Fluid retention is common after elective pancreatic resection, and its associated with an increased rate of postoperative complications.</p>}},
author = {{Åkerberg, Daniel and Ansari, Daniel and Bergenfeldt, Magnus and Andersson, Roland and Tingstedt, Bobby}},
issn = {{1365-182X}},
language = {{eng}},
number = {{12}},
pages = {{1784--1789}},
publisher = {{Elsevier}},
series = {{HPB}},
title = {{Early postoperative fluid retention is a strong predictor for complications after pancreatoduodenectomy}},
url = {{http://dx.doi.org/10.1016/j.hpb.2019.05.003}},
doi = {{10.1016/j.hpb.2019.05.003}},
volume = {{21}},
year = {{2019}},
}