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Eubacterium bacteremia – a retrospective observational study of a seldom found anaerobic pathogen

Bläckberg, Anna LU ; Holm, Karin LU ; Liderot, Karin ; Nilson, Bo LU orcid and Sunnerhagen, Torgny LU orcid (2024) In Diagnostic Microbiology and Infectious Disease 108(4).
Abstract
Background
Human infections due to Eubacterium are rare and knowledge of the condition is limited. This study aimed to describe clinical characteristics and outcome in patients with Eubacterium bacteremia.

Methods
Episodes of Eubacterium bacteremia were identified through the clinical microbiology laboratory in Lund, Sweden. Medical records were retrospectively reviewed. Blood isolates of Eubacterium were collected and antibiotic susceptibility testing was performed with agar dilution.

Results
Seventeen patients with Eubacterium bacteremia were identified of whom six had monomicrobial bacteremia. The incidence was 1.7 cases of Eubacterium bacteremia per million inhabitants and year. The median age was 67 years... (More)
Background
Human infections due to Eubacterium are rare and knowledge of the condition is limited. This study aimed to describe clinical characteristics and outcome in patients with Eubacterium bacteremia.

Methods
Episodes of Eubacterium bacteremia were identified through the clinical microbiology laboratory in Lund, Sweden. Medical records were retrospectively reviewed. Blood isolates of Eubacterium were collected and antibiotic susceptibility testing was performed with agar dilution.

Results
Seventeen patients with Eubacterium bacteremia were identified of whom six had monomicrobial bacteremia. The incidence was 1.7 cases of Eubacterium bacteremia per million inhabitants and year. The median age was 67 years (interquartile range 63-79 years), and six patients had some form of malignancy. Most of the patients an abdominal focus of infection and the 30-day mortality was low (n=1).

Conclusions
Invasive infections with Eubacterium have a low incidence. The condition has a low mortality and an abdominal focus of infection, and malignancy, is common. (Less)
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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Diagnostic Microbiology and Infectious Disease
volume
108
issue
4
article number
116185
publisher
Elsevier
external identifiers
  • scopus:85182663125
  • pmid:38232640
ISSN
1879-0070
DOI
10.1016/j.diagmicrobio.2024.116185
language
English
LU publication?
yes
id
cc562081-e2c9-405a-af89-716996f31ffe
date added to LUP
2024-01-13 11:11:21
date last changed
2024-04-14 03:00:04
@article{cc562081-e2c9-405a-af89-716996f31ffe,
  abstract     = {{Background<br/>Human infections due to Eubacterium are rare and knowledge of the condition is limited. This study aimed to describe clinical characteristics and outcome in patients with Eubacterium bacteremia.<br/><br/>Methods<br/>Episodes of Eubacterium bacteremia were identified through the clinical microbiology laboratory in Lund, Sweden. Medical records were retrospectively reviewed. Blood isolates of Eubacterium were collected and antibiotic susceptibility testing was performed with agar dilution.<br/><br/>Results<br/>Seventeen patients with Eubacterium bacteremia were identified of whom six had monomicrobial bacteremia. The incidence was 1.7 cases of Eubacterium bacteremia per million inhabitants and year. The median age was 67 years (interquartile range 63-79 years), and six patients had some form of malignancy. Most of the patients an abdominal focus of infection and the 30-day mortality was low (n=1).<br/><br/>Conclusions<br/>Invasive infections with Eubacterium have a low incidence. The condition has a low mortality and an abdominal focus of infection, and malignancy, is common.}},
  author       = {{Bläckberg, Anna and Holm, Karin and Liderot, Karin and Nilson, Bo and Sunnerhagen, Torgny}},
  issn         = {{1879-0070}},
  language     = {{eng}},
  number       = {{4}},
  publisher    = {{Elsevier}},
  series       = {{Diagnostic Microbiology and Infectious Disease}},
  title        = {{Eubacterium bacteremia – a retrospective observational study of a seldom found anaerobic pathogen}},
  url          = {{https://lup.lub.lu.se/search/files/171090950/Eubacterium_bacteremia_a_retrospective_observational_study_of_a_seldom_found_anaerobic_pathogen.pdf}},
  doi          = {{10.1016/j.diagmicrobio.2024.116185}},
  volume       = {{108}},
  year         = {{2024}},
}