Sex and age differences in the patient-reported outcome measures and adherence to an osteoarthritis digital self-management intervention
(2024) In Osteoarthritis and Cartilage Open 6(1).- Abstract
- Objective
To explore sex and age differences in Patient-Reported Outcomes Measures (PROMs) and adherence to digital osteoarthritis (OA) self-management intervention.
Methods
A register-based study with data from an OA digital self-management intervention. PROMs and adherence were collected at baseline and/or 3 month follow-up: ‘pain intensity’ in hip/knee (best/worst: 0–10), ‘activity impairments' (best/worst: 0–10), ‘overall health’ perception (worst/best: 0–10), ‘physical function’ (30-s chair stand test), ‘health-related quality of life’ (EQ-5D-5L index score; worst/best: 0.243–0.976), the subscales and total scores of the Knee Injury/Hip Disability and Osteoarthritis Outcome Score (KOOS/HOOS-12; worst/best: 0–100), ‘fear... (More) - Objective
To explore sex and age differences in Patient-Reported Outcomes Measures (PROMs) and adherence to digital osteoarthritis (OA) self-management intervention.
Methods
A register-based study with data from an OA digital self-management intervention. PROMs and adherence were collected at baseline and/or 3 month follow-up: ‘pain intensity’ in hip/knee (best/worst: 0–10), ‘activity impairments' (best/worst: 0–10), ‘overall health’ perception (worst/best: 0–10), ‘physical function’ (30-s chair stand test), ‘health-related quality of life’ (EQ-5D-5L index score; worst/best: 0.243–0.976), the subscales and total scores of the Knee Injury/Hip Disability and Osteoarthritis Outcome Score (KOOS/HOOS-12; worst/best: 0–100), ‘fear of movement’ (yes/no), ‘walking difficulties' (yes/no), ‘programme adherence’ (0–100 % and ≥80 % [yes/no]), ‘patient acceptable symptom state’ (PASS; yes/no), and ‘treatment failure’ (those who answered no to PASS question and thought the treatment failed [yes/no]). We used linear/logistic regression to calculate mean/risk differences in the PROMs and adherence levels among sex and age groups at 3-month follow-up. We employed entropy balancing to explore the contributions of baseline characteristics and different covariates to the sex/age differences.
Results
We included 14,610 participants (mean (SD) age: 64.1 (9.1), 75.5 % females). Females generally reported better outcomes than males. Participants aged ≥70 had greater activity impairments, lower KOOS/HOOS-pain/function scores, more walking difficulties, less fear of movement and higher adherence than those <70. However, these differences were small and not likely clinically relevant.
Conclusion
No clinically relevant differences in PROMs and adherence were found among sex/age groups in this digital OA programme, suggesting that sex/age seemed not to impact the outcomes of this intervention. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/cc97fed3-f454-400e-9e94-fdb6a40f2289
- author
- Battista, Simone LU ; Lohmander, L Stefan LU ; Dell’isola, Andrea LU ; Dahlberg, Leif E LU and Kiadaliri, Ali LU
- organization
-
- Lund OsteoArthritis Division - Clinical Epidemiology Unit (research group)
- EpiHealth: Epidemiology for Health
- Lund OsteoArthritis Division - Molecular marker research group (research group)
- Orthopaedics (Lund)
- LU Profile Area: Proactive Ageing
- Lund OsteoArthritis Division - From molecule to clinical implementation (research group)
- Centre for Economic Demography
- publishing date
- 2024-03-01
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Osteoarthritis and Cartilage Open
- volume
- 6
- issue
- 1
- article number
- 100437
- publisher
- Elsevier
- external identifiers
-
- scopus:85183948885
- ISSN
- 2665-9131
- DOI
- 10.1016/j.ocarto.2024.100437
- language
- English
- LU publication?
- yes
- id
- cc97fed3-f454-400e-9e94-fdb6a40f2289
- date added to LUP
- 2024-02-05 09:39:17
- date last changed
- 2024-03-12 14:29:47
@article{cc97fed3-f454-400e-9e94-fdb6a40f2289, abstract = {{Objective<br/>To explore sex and age differences in Patient-Reported Outcomes Measures (PROMs) and adherence to digital osteoarthritis (OA) self-management intervention.<br/>Methods<br/>A register-based study with data from an OA digital self-management intervention. PROMs and adherence were collected at baseline and/or 3 month follow-up: ‘pain intensity’ in hip/knee (best/worst: 0–10), ‘activity impairments' (best/worst: 0–10), ‘overall health’ perception (worst/best: 0–10), ‘physical function’ (30-s chair stand test), ‘health-related quality of life’ (EQ-5D-5L index score; worst/best: 0.243–0.976), the subscales and total scores of the Knee Injury/Hip Disability and Osteoarthritis Outcome Score (KOOS/HOOS-12; worst/best: 0–100), ‘fear of movement’ (yes/no), ‘walking difficulties' (yes/no), ‘programme adherence’ (0–100 % and ≥80 % [yes/no]), ‘patient acceptable symptom state’ (PASS; yes/no), and ‘treatment failure’ (those who answered no to PASS question and thought the treatment failed [yes/no]). We used linear/logistic regression to calculate mean/risk differences in the PROMs and adherence levels among sex and age groups at 3-month follow-up. We employed entropy balancing to explore the contributions of baseline characteristics and different covariates to the sex/age differences.<br/>Results<br/>We included 14,610 participants (mean (SD) age: 64.1 (9.1), 75.5 % females). Females generally reported better outcomes than males. Participants aged ≥70 had greater activity impairments, lower KOOS/HOOS-pain/function scores, more walking difficulties, less fear of movement and higher adherence than those <70. However, these differences were small and not likely clinically relevant.<br/>Conclusion<br/>No clinically relevant differences in PROMs and adherence were found among sex/age groups in this digital OA programme, suggesting that sex/age seemed not to impact the outcomes of this intervention.}}, author = {{Battista, Simone and Lohmander, L Stefan and Dell’isola, Andrea and Dahlberg, Leif E and Kiadaliri, Ali}}, issn = {{2665-9131}}, language = {{eng}}, month = {{03}}, number = {{1}}, publisher = {{Elsevier}}, series = {{Osteoarthritis and Cartilage Open}}, title = {{Sex and age differences in the patient-reported outcome measures and adherence to an osteoarthritis digital self-management intervention}}, url = {{http://dx.doi.org/10.1016/j.ocarto.2024.100437}}, doi = {{10.1016/j.ocarto.2024.100437}}, volume = {{6}}, year = {{2024}}, }