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Autoimmunity in Long Covid and POTS

El-Rhermoul, Fatema-Zahra ; Fedorowski, Artur LU orcid ; Eardley, Philip ; Taraborrelli, Patricia ; Panagopoulos, Dimitrios ; Sutton, Richard LU ; Lim, Phang Boon and Dani, Melanie (2023) In Oxford Open Immunology 4(1). p.1-9
Abstract

Orthostatic intolerance and other autonomic dysfunction syndromes are emerging as distinct symptom clusters in Long Covid. Often accompanying these are common, multi-system constitutional features such as fatigue, malaise and skin rashes which can signify generalized immune dysregulation. At the same time, multiple autoantibodies are identified in both Covid-related autonomic disorders and non-Covid autonomic disorders, implying a possible underlying autoimmune pathology. The lack of specificity of these findings precludes direct interpretations of cause and association, but their prevalence with its supporting evidence is compelling.

Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
in
Oxford Open Immunology
volume
4
issue
1
article number
iqad002
pages
1 - 9
publisher
Oxford University Press
external identifiers
  • scopus:85161490491
  • pmid:37255928
ISSN
2633-6960
DOI
10.1093/oxfimm/iqad002
language
English
LU publication?
no
additional info
© The Author(s) 2023. Published by Oxford University Press.
id
cdf92ff1-7a74-4e49-b4b4-a38166b62141
date added to LUP
2023-06-03 09:39:01
date last changed
2024-04-19 22:35:19
@article{cdf92ff1-7a74-4e49-b4b4-a38166b62141,
  abstract     = {{<p>Orthostatic intolerance and other autonomic dysfunction syndromes are emerging as distinct symptom clusters in Long Covid. Often accompanying these are common, multi-system constitutional features such as fatigue, malaise and skin rashes which can signify generalized immune dysregulation. At the same time, multiple autoantibodies are identified in both Covid-related autonomic disorders and non-Covid autonomic disorders, implying a possible underlying autoimmune pathology. The lack of specificity of these findings precludes direct interpretations of cause and association, but their prevalence with its supporting evidence is compelling.</p>}},
  author       = {{El-Rhermoul, Fatema-Zahra and Fedorowski, Artur and Eardley, Philip and Taraborrelli, Patricia and Panagopoulos, Dimitrios and Sutton, Richard and Lim, Phang Boon and Dani, Melanie}},
  issn         = {{2633-6960}},
  language     = {{eng}},
  month        = {{06}},
  number       = {{1}},
  pages        = {{1--9}},
  publisher    = {{Oxford University Press}},
  series       = {{Oxford Open Immunology}},
  title        = {{Autoimmunity in Long Covid and POTS}},
  url          = {{http://dx.doi.org/10.1093/oxfimm/iqad002}},
  doi          = {{10.1093/oxfimm/iqad002}},
  volume       = {{4}},
  year         = {{2023}},
}