Skip to main content

Lund University Publications

LUND UNIVERSITY LIBRARIES

Safety of pancreatic resection in the elderly : a retrospective analysis of 556 patients

Ansari, Daniel LU ; Aronsson, Linus LU ; Fredriksson, Joakim ; Andersson, Bodil LU orcid and Andersson, Roland LU (2016) In Annals of Gastroenterology 29(2). p.5-221
Abstract

BACKGROUND: The safety of pancreatic resection for elderly patients is still controversial. We examined the postoperative morbidity and mortality in patients aged 75 years or more undergoing pancreatic resection.

METHODS: Patients undergoing pancreatic resection were studied retrospectively and the outcomes were compared between patients aged <75 and ≥75 years.

RESULTS: Of the 556 patients enrolled, 78 (14%) were ≥75 years old. Elderly patients had significantly more co-morbidities, especially cardiovascular pathology (P=0.005). Also, elderly patients had significantly lower body mass index prior to surgery (P=0.005). There were no significant differences in terms of surgical procedures and tumor types between age groups.... (More)

BACKGROUND: The safety of pancreatic resection for elderly patients is still controversial. We examined the postoperative morbidity and mortality in patients aged 75 years or more undergoing pancreatic resection.

METHODS: Patients undergoing pancreatic resection were studied retrospectively and the outcomes were compared between patients aged <75 and ≥75 years.

RESULTS: Of the 556 patients enrolled, 78 (14%) were ≥75 years old. Elderly patients had significantly more co-morbidities, especially cardiovascular pathology (P=0.005). Also, elderly patients had significantly lower body mass index prior to surgery (P=0.005). There were no significant differences in terms of surgical procedures and tumor types between age groups. The incidence of postoperative pancreatic fistula grade A was significantly lower in the elderly group (P=0.022), but no significant differences were noted in the overall morbidity or the incidence of postpancreatectomy hemorrhage, delayed gastric emptying, bile leakage, cardiac complications, pulmonary complications or septic complications. The 30-day mortality rate was similar between groups (0.8% vs. 1.3%; P=0.532).

CONCLUSION: Pancreatic resection is a safe option for selected elderly patients. Our study confirms that age alone should not preclude potentially curative surgical therapy.

(Less)
Please use this url to cite or link to this publication:
author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Annals of Gastroenterology
volume
29
issue
2
pages
5 pages
publisher
Hellenic Society of Gastroenterology
external identifiers
  • scopus:84962366074
  • wos:000378933700017
  • pmid:27065736
ISSN
1108-7471
DOI
10.20524/aog.2016.0016
project
Pancreatic cancer
language
English
LU publication?
yes
id
cea5c9ef-a995-47be-8928-c530bc06aba6
date added to LUP
2016-05-04 08:44:41
date last changed
2024-05-17 02:13:27
@article{cea5c9ef-a995-47be-8928-c530bc06aba6,
  abstract     = {{<p>BACKGROUND: The safety of pancreatic resection for elderly patients is still controversial. We examined the postoperative morbidity and mortality in patients aged 75 years or more undergoing pancreatic resection.</p><p>METHODS: Patients undergoing pancreatic resection were studied retrospectively and the outcomes were compared between patients aged &lt;75 and ≥75 years.</p><p>RESULTS: Of the 556 patients enrolled, 78 (14%) were ≥75 years old. Elderly patients had significantly more co-morbidities, especially cardiovascular pathology (P=0.005). Also, elderly patients had significantly lower body mass index prior to surgery (P=0.005). There were no significant differences in terms of surgical procedures and tumor types between age groups. The incidence of postoperative pancreatic fistula grade A was significantly lower in the elderly group (P=0.022), but no significant differences were noted in the overall morbidity or the incidence of postpancreatectomy hemorrhage, delayed gastric emptying, bile leakage, cardiac complications, pulmonary complications or septic complications. The 30-day mortality rate was similar between groups (0.8% vs. 1.3%; P=0.532).</p><p>CONCLUSION: Pancreatic resection is a safe option for selected elderly patients. Our study confirms that age alone should not preclude potentially curative surgical therapy.</p>}},
  author       = {{Ansari, Daniel and Aronsson, Linus and Fredriksson, Joakim and Andersson, Bodil and Andersson, Roland}},
  issn         = {{1108-7471}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{5--221}},
  publisher    = {{Hellenic Society of Gastroenterology}},
  series       = {{Annals of Gastroenterology}},
  title        = {{Safety of pancreatic resection in the elderly : a retrospective analysis of 556 patients}},
  url          = {{http://dx.doi.org/10.20524/aog.2016.0016}},
  doi          = {{10.20524/aog.2016.0016}},
  volume       = {{29}},
  year         = {{2016}},
}