Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study
(2012) In Age and Ageing 41(3). p.351-357- Abstract
- Objective: assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Design: individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. Subjects: a total of 5,764 individuals, 57.7% women, born 1907-35, mean age 77. Method: four groups with a verified fracture status were used; vertebral fractures, other osteoporotic fractures excluding vertebral, non-osteoporotic fractures and not-fractured were compared and analysed for the effect on mobility, strength, QoL, ADL, co-morbidity and hospitalisation. Results: worst performance on functional... (More)
- Objective: assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Design: individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. Subjects: a total of 5,764 individuals, 57.7% women, born 1907-35, mean age 77. Method: four groups with a verified fracture status were used; vertebral fractures, other osteoporotic fractures excluding vertebral, non-osteoporotic fractures and not-fractured were compared and analysed for the effect on mobility, strength, QoL, ADL, co-morbidity and hospitalisation. Results: worst performance on functional tests was in the vertebral fracture group for women (P < 0.0001) and the other osteoporotic fractures group for men (P < 0.05). Both vertebral and other osteoporotic fractures, showed an increased risk of hospitalisation, HR = 1.4 (95% CI: 1.3-1.7) and 1.2 (95% CI: 1.1-1.2) respectively (P < 0.0001). Individuals with vertebral fractures had 50% (P < 0.0001) longer hospitalisation than not-fractured and 33% (P < 0.002) longer than the other osteoporotic fractures group. Conclusion: individuals with a history of clinical vertebral fracture seem to carry the greatest health burden compared with other fracture groups, emphasising the attention which should be given to those individuals. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/2551539
- author
- Siggeirsdottir, Kristin ; Aspelund, Thor ; Jonsson, Brynjolfur LU ; Mogensen, Brynjolfur ; Launer, Lenore J. ; Harris, Tamara B. ; Sigurdsson, Gunnar and Gudnason, Vilmundur
- organization
- publishing date
- 2012
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- vertebral fracture, health burden, osteoporotic fracture, strength, ADL, quality of life, mobility, elderly
- in
- Age and Ageing
- volume
- 41
- issue
- 3
- pages
- 351 - 357
- publisher
- Oxford University Press
- external identifiers
-
- wos:000303335000013
- scopus:84860510776
- ISSN
- 1468-2834
- DOI
- 10.1093/ageing/afs003
- language
- English
- LU publication?
- yes
- id
- d085e768-99b3-4ce6-822e-963985fcc02e (old id 2551539)
- date added to LUP
- 2016-04-01 10:24:34
- date last changed
- 2024-06-03 18:37:26
@article{d085e768-99b3-4ce6-822e-963985fcc02e,
abstract = {{Objective: assess the effect of clinical vertebral and other osteoporotic fractures on function and the subsequent risk of hospitalisation. Design: individuals from the prospective population-based cohort study Age, Gene/Environment Susceptibility (AGES)-Reykjavik study were examined between 2002 and 2006 and followed up for 5.4 years. Subjects: a total of 5,764 individuals, 57.7% women, born 1907-35, mean age 77. Method: four groups with a verified fracture status were used; vertebral fractures, other osteoporotic fractures excluding vertebral, non-osteoporotic fractures and not-fractured were compared and analysed for the effect on mobility, strength, QoL, ADL, co-morbidity and hospitalisation. Results: worst performance on functional tests was in the vertebral fracture group for women (P < 0.0001) and the other osteoporotic fractures group for men (P < 0.05). Both vertebral and other osteoporotic fractures, showed an increased risk of hospitalisation, HR = 1.4 (95% CI: 1.3-1.7) and 1.2 (95% CI: 1.1-1.2) respectively (P < 0.0001). Individuals with vertebral fractures had 50% (P < 0.0001) longer hospitalisation than not-fractured and 33% (P < 0.002) longer than the other osteoporotic fractures group. Conclusion: individuals with a history of clinical vertebral fracture seem to carry the greatest health burden compared with other fracture groups, emphasising the attention which should be given to those individuals.}},
author = {{Siggeirsdottir, Kristin and Aspelund, Thor and Jonsson, Brynjolfur and Mogensen, Brynjolfur and Launer, Lenore J. and Harris, Tamara B. and Sigurdsson, Gunnar and Gudnason, Vilmundur}},
issn = {{1468-2834}},
keywords = {{vertebral fracture; health burden; osteoporotic fracture; strength; ADL; quality of life; mobility; elderly}},
language = {{eng}},
number = {{3}},
pages = {{351--357}},
publisher = {{Oxford University Press}},
series = {{Age and Ageing}},
title = {{Effect of vertebral fractures on function, quality of life and hospitalisation the AGES-Reykjavik study}},
url = {{http://dx.doi.org/10.1093/ageing/afs003}},
doi = {{10.1093/ageing/afs003}},
volume = {{41}},
year = {{2012}},
}