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Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Toussaint, Laura ; Brandal, Petter ; Embring, Anna ; Engellau, Jacob LU ; Evensen, Morten Egeberg ; Griskeviskius, Romualdas ; Hansen, Jolanta ; Hietala, Henna ; Wickart Johansson, Gun and Jørgensen, Morten , et al. (2022) In Acta Oncologica 61(2). p.235-238
Abstract
Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in... (More)
Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours. (Less)
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author collaboration
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Acta Oncologica
volume
61
issue
2
pages
4 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85122663205
  • pmid:34970940
ISSN
0284-186X
DOI
10.1080/0284186X.2021.2022202
language
English
LU publication?
yes
id
d2e82247-9f7b-416f-8fb1-abbd685e8c24
date added to LUP
2022-03-07 14:05:12
date last changed
2024-04-12 09:22:20
@article{d2e82247-9f7b-416f-8fb1-abbd685e8c24,
  abstract     = {{Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.}},
  author       = {{Toussaint, Laura and Brandal, Petter and Embring, Anna and Engellau, Jacob and Evensen, Morten Egeberg and Griskeviskius, Romualdas and Hansen, Jolanta and Hietala, Henna and Wickart Johansson, Gun and Jørgensen, Morten and Kramer, Paul Heinz and Kristensen, Ingrid and Lehtio, Kaisa and Magelssen, Henriette and Maraldo, Maja Vestmø and Marienhagen, Kirsten and Martinsson, Ulla and Nilsson, Kristina and Peters, Sarah and Plaude, Sandija and Seiersen, Klaus and Sendiuliene, Daiva and Smulders, Bob and Edvardsen, Tone and Søbstad, Johan Martin and Taheri, Zarah and Vaalavirta, Leila and Vestergaard, Anne and Timmermann, Beate and Lassen-Ramshad, Yasmin}},
  issn         = {{0284-186X}},
  language     = {{eng}},
  number       = {{2}},
  pages        = {{235--238}},
  publisher    = {{Taylor & Francis}},
  series       = {{Acta Oncologica}},
  title        = {{Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma}},
  url          = {{http://dx.doi.org/10.1080/0284186X.2021.2022202}},
  doi          = {{10.1080/0284186X.2021.2022202}},
  volume       = {{61}},
  year         = {{2022}},
}