Delayed cochlear implantation in post-meningitic deafness and hereditary complement C2 deficiency
(2017) In International Journal of Pediatric Otorhinolaryngology Extra 15. p.4-8- Abstract
We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing... (More)
We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing the literature.
(Less)
- author
- Di Berardino, Federica ; Truedsson, Lennart LU and Zanetti, Diego
- organization
- publishing date
- 2017-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Adolescence, C2, Cochlear implantation, Complement deficiency, Immunological, Meningitis
- in
- International Journal of Pediatric Otorhinolaryngology Extra
- volume
- 15
- pages
- 5 pages
- publisher
- Elsevier
- external identifiers
-
- wos:000418749600002
- scopus:85007553549
- ISSN
- 1871-4048
- DOI
- 10.1016/j.pedex.2016.11.002
- language
- English
- LU publication?
- yes
- id
- d38e82af-0460-46a6-b2ed-f14b0791c768
- date added to LUP
- 2017-01-13 15:47:19
- date last changed
- 2024-03-07 20:26:06
@article{d38e82af-0460-46a6-b2ed-f14b0791c768,
abstract = {{<p>We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing the literature.</p>}},
author = {{Di Berardino, Federica and Truedsson, Lennart and Zanetti, Diego}},
issn = {{1871-4048}},
keywords = {{Adolescence; C2; Cochlear implantation; Complement deficiency; Immunological; Meningitis}},
language = {{eng}},
month = {{01}},
pages = {{4--8}},
publisher = {{Elsevier}},
series = {{International Journal of Pediatric Otorhinolaryngology Extra}},
title = {{Delayed cochlear implantation in post-meningitic deafness and hereditary complement C2 deficiency}},
url = {{http://dx.doi.org/10.1016/j.pedex.2016.11.002}},
doi = {{10.1016/j.pedex.2016.11.002}},
volume = {{15}},
year = {{2017}},
}