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Delayed cochlear implantation in post-meningitic deafness and hereditary complement C2 deficiency

Di Berardino, Federica; Truedsson, Lennart LU and Zanetti, Diego (2017) In International Journal of Pediatric Otorhinolaryngology Extra 15. p.4-8
Abstract

We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing... (More)

We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing the literature.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Adolescence, C2, Cochlear implantation, Complement deficiency, Immunological, Meningitis
in
International Journal of Pediatric Otorhinolaryngology Extra
volume
15
pages
5 pages
publisher
Elsevier
external identifiers
  • scopus:85007553549
  • wos:000418749600002
ISSN
1871-4048
DOI
10.1016/j.pedex.2016.11.002
language
English
LU publication?
yes
id
d38e82af-0460-46a6-b2ed-f14b0791c768
date added to LUP
2017-01-13 15:47:19
date last changed
2018-01-16 13:22:46
@article{d38e82af-0460-46a6-b2ed-f14b0791c768,
  abstract     = {<p>We report the case of an adolescent with post-verbal severe/profound sensorineural hearing loss, occurring as a consequence of two bouts of pneumococcal meningitis at 12 and 32 months of age. A possible immunodeficiency was investigated, revealing hereditary complement C2 deficiency (C2D). Given the insufficient benefit from high-power hearing aids, the boy received a cochlear implant (CI) at age 12. Despite the long interval of partial hearing deprivation and the post-meningitic etiology, improvement in open-set speech perception and quality of life were observed. The C2D did not favour post-operative infections nor meningitis recurrence. The risks and benefit of CI in this peculiar clinical circumstance are discussed after reviewing the literature.</p>},
  author       = {Di Berardino, Federica and Truedsson, Lennart and Zanetti, Diego},
  issn         = {1871-4048},
  keyword      = {Adolescence,C2,Cochlear implantation,Complement deficiency,Immunological,Meningitis},
  language     = {eng},
  month        = {01},
  pages        = {4--8},
  publisher    = {Elsevier},
  series       = {International Journal of Pediatric Otorhinolaryngology Extra},
  title        = {Delayed cochlear implantation in post-meningitic deafness and hereditary complement C2 deficiency},
  url          = {http://dx.doi.org/10.1016/j.pedex.2016.11.002},
  volume       = {15},
  year         = {2017},
}