Characterization of neurotrophic activity in the silicone-chamber model for nerve regeneration
(1995) In Journal of Reconstructive Microsurgery 11(3). p.231-235- Abstract
In the present study, the authors reevaluated the temporal course and properties of neurotrophic activities present in the fluid accumulating in the silicone-chamber model for nerve regeneration. The fluid collected from silicone chambers was tested in four different dissociated neuronal cell cultures. Furthermore, the activity of the chamber fluid was examined, using a cell blot technique. There was one major peak of neurotrophic activity and this activity peaked early, about 3 to 6 hr after nerve injury. Results also indicate that the chamber fluid contains at least two types of neurotrophic activities, namely nerve growth factor and ciliary neurotrophic factor.
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https://lup.lub.lu.se/record/d6540184-fd41-465f-a477-e3ea08e46da9
- author
- Danielsen, N LU and Varon, S
- organization
- publishing date
- 1995-05
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Animals, Cells, Cultured, Ciliary Neurotrophic Factor, Diffusion Chambers, Culture, Female, Nerve Growth Factors, Nerve Regeneration, Nerve Tissue Proteins, Neurons, Rats, Rats, Sprague-Dawley, Sciatic Nerve, Journal Article, Research Support, Non-U.S. Gov't
- in
- Journal of Reconstructive Microsurgery
- volume
- 11
- issue
- 3
- pages
- 5 pages
- publisher
- Georg Thieme Verlag
- external identifiers
-
- pmid:7650650
- scopus:0029065435
- ISSN
- 0743-684X
- DOI
- 10.1055/s-2007-1006537
- language
- English
- LU publication?
- yes
- id
- d6540184-fd41-465f-a477-e3ea08e46da9
- date added to LUP
- 2017-10-13 13:40:03
- date last changed
- 2024-01-14 07:23:05
@article{d6540184-fd41-465f-a477-e3ea08e46da9, abstract = {{<p>In the present study, the authors reevaluated the temporal course and properties of neurotrophic activities present in the fluid accumulating in the silicone-chamber model for nerve regeneration. The fluid collected from silicone chambers was tested in four different dissociated neuronal cell cultures. Furthermore, the activity of the chamber fluid was examined, using a cell blot technique. There was one major peak of neurotrophic activity and this activity peaked early, about 3 to 6 hr after nerve injury. Results also indicate that the chamber fluid contains at least two types of neurotrophic activities, namely nerve growth factor and ciliary neurotrophic factor.</p>}}, author = {{Danielsen, N and Varon, S}}, issn = {{0743-684X}}, keywords = {{Animals; Cells, Cultured; Ciliary Neurotrophic Factor; Diffusion Chambers, Culture; Female; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurons; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Journal Article; Research Support, Non-U.S. Gov't}}, language = {{eng}}, number = {{3}}, pages = {{231--235}}, publisher = {{Georg Thieme Verlag}}, series = {{Journal of Reconstructive Microsurgery}}, title = {{Characterization of neurotrophic activity in the silicone-chamber model for nerve regeneration}}, url = {{http://dx.doi.org/10.1055/s-2007-1006537}}, doi = {{10.1055/s-2007-1006537}}, volume = {{11}}, year = {{1995}}, }