Understanding inhomogeneous MT (ihMT) in multi-parameter mapping of human brain: Towards larger ihMT, higher resolution, and influence of T1d
(2022) In Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition 30.- Abstract
- Inhomogenous Magnetization Transfer (ihMT), the differential response to irradiation at single and dual frequency offsets, is more complex than MT approaches. Expressing ihMT in terms of MT-saturation (ihMTsat) is a first step to quantification as it corrects for underlying T and B . Larger ihMTsat was observed for smaller frequency offsets, which is explained using MTsat as proxy for bound pool saturation. For longer TR, ihMTsat increased faster than MTsat indicating recovery of dipolar order as ihMTsat increased super-linearly to 1.1pu in WM and 0.2pu in GM at TR=52ms. ihMTsat mapping in vivo was performed at 1.3mm isotropic resolution.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/d6788134-ad32-4b15-bbb9-d52dace57ab0
- author
- Helms, Gunther LU ; Vaculčiaková, Lenka ; Pine, Kerrin J ; Möller, Harald E and Weiskopf, Nikolaus
- organization
- publishing date
- 2022-04-22
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition
- series title
- Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition
- volume
- 30
- article number
- 2705
- publisher
- International Society for Magnetic Resonance in Medicine
- ISSN
- 1545-4428
- language
- English
- LU publication?
- yes
- id
- d6788134-ad32-4b15-bbb9-d52dace57ab0
- alternative location
- https://index.mirasmart.com/ISMRM2022/PDFfiles/2705.html
- date added to LUP
- 2022-07-13 12:41:22
- date last changed
- 2022-11-29 08:07:29
@inproceedings{d6788134-ad32-4b15-bbb9-d52dace57ab0, abstract = {{Inhomogenous Magnetization Transfer (ihMT), the differential response to irradiation at single and dual frequency offsets, is more complex than MT approaches. Expressing ihMT in terms of MT-saturation (ihMTsat) is a first step to quantification as it corrects for underlying T and B . Larger ihMTsat was observed for smaller frequency offsets, which is explained using MTsat as proxy for bound pool saturation. For longer TR, ihMTsat increased faster than MTsat indicating recovery of dipolar order as ihMTsat increased super-linearly to 1.1pu in WM and 0.2pu in GM at TR=52ms. ihMTsat mapping in vivo was performed at 1.3mm isotropic resolution.}}, author = {{Helms, Gunther and Vaculčiaková, Lenka and Pine, Kerrin J and Möller, Harald E and Weiskopf, Nikolaus}}, booktitle = {{Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition}}, issn = {{1545-4428}}, language = {{eng}}, month = {{04}}, publisher = {{International Society for Magnetic Resonance in Medicine}}, series = {{Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition}}, title = {{Understanding inhomogeneous MT (ihMT) in multi-parameter mapping of human brain: Towards larger ihMT, higher resolution, and influence of T<sub>1d</sub>}}, url = {{https://index.mirasmart.com/ISMRM2022/PDFfiles/2705.html}}, volume = {{30}}, year = {{2022}}, }